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Small molecules

Toward the Discovery of Vaccine Adjuvants: Coupling In Silico Screening and In Vitro Analysis of Antagonist Binding to Human and Mouse CCR4 Receptors

Matthew N. Davies, Jagadeesh Bayry, Elma Z. Tchilian, Janakiraman Vani, Melkote S. Shaila, Emily K. Forbes, Simon J. Draper, Peter C. L. Beverley, David F. Tough, Darren R. Flower

published 30 Nov 2009

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Tyrosine, Cysteine, and S-Adenosyl Methionine Stimulate In Vitro [FeFe] Hydrogenase Activation

Jon M. Kuchenreuther, James A. Stapleton, James R. Swartz

published 26 Oct 2009

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NSC23925, Identified in a High-Throughput Cell-Based Screen, Reverses Multidrug Resistance

Zhenfeng Duan, Edwin Choy, Francis J. Hornicek

published 12 Oct 2009

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The Small Molecule Inhibitor QLT0267 Radiosensitizes Squamous Cell Carcinoma Cells of the Head and Neck

Iris Eke, Franziska Leonhardt, Katja Storch, Stephanie Hehlgans, Nils Cordes

published 30 Jul 2009

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Identification and Characterization of Inhibitors of Human Apurinic/apyrimidinic Endonuclease APE1

Anton Simeonov, Avanti Kulkarni, Dorjbal Dorjsuren, Ajit Jadhav, Min Shen, Daniel R. McNeill, Christopher P. Austin, David M. Wilson III

published 01 Jun 2009

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MGL2⁺ Dermal Dendritic Cells Are Sufficient to Initiate Contact Hypersensitivity In Vivo

Yosuke Kumamoto, Kaori Denda-Nagai, Satoshi Aida, Nobuaki Higashi, Tatsuro Irimura

published 19 May 2009

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Dynamics of Uptake and Metabolism of Small Molecules in Cellular Response Systems

Maria Werner, Szabolcs Semsey, Kim Sneppen, Sandeep Krishna

published 17 Mar 2009

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Computer Aided Identification of Small Molecules Disrupting uPAR/α5β1- Integrin Interaction: A New Paradigm for Metastasis Prevention

Pratima Chaurasia, Mihaly Mezei, Ming-Ming Zhou, Liliana Ossowski

published 26 Feb 2009

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Discovery of a Novel Activator of KCNQ1-KCNE1 K⁺ Channel Complexes

Karen Mruk, William R. Kobertz

published 21 Jan 2009

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Small Molecule, Non-Peptide p75^NTR Ligands Inhibit Aβ-Induced Neurodegeneration and Synaptic Impairment

Tao Yang, Juliet K. Knowles, Qun Lu, Hong Zhang, Ottavio Arancio, Laura A. Moore, Timothy Chang, Qian Wang, Katrin Andreasson, Jayakumar Rajadas, Gerald G. Fuller, Youmei Xie, Stephen M. Massa, Frank M. Longo

published 03 Nov 2008

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Dynamical Systems Analysis of Mitochondrial BAK Activation Kinetics Predicts Resistance to BH3 Domains

Claire Grills, Nyree Crawford, Alex Chacko, Patrick G. Johnston, Francesca O'Rourke, Dean A. Fennell

published 22 Aug 2008

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Dorsomorphin, a Selective Small Molecule Inhibitor of BMP Signaling, Promotes Cardiomyogenesis in Embryonic Stem Cells

Jijun Hao, Marie A. Daleo, Clare K. Murphy, Paul B. Yu, Joshua N. Ho, Jianyong Hu, Randall T. Peterson, Antonis K. Hatzopoulos, Charles C. Hong

published 06 Aug 2008

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Identification of a Novel Retinoid by Small Molecule Screening with Zebrafish Embryos

Chetana Sachidanandan, Jing-Ruey J. Yeh, Quinn P. Peterson, Randall T. Peterson

published 09 Apr 2008

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