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Small molecules

Simultaneous Induction of Non-Canonical Autophagy and Apoptosis in Cancer Cells by ROS-Dependent ERK and JNK Activation

Chew Hooi Wong, Kartini Bte Iskandar, Sanjiv Kumar Yadav, Jayshree L. Hirpara, Thomas Loh, Shazib Pervaiz

published 02 Apr 2010

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Atomic Analysis of Protein-Protein Interfaces with Known Inhibitors: The 2P2I Database

Raphaël Bourgeas, Marie-Jeanne Basse, Xavier Morelli, Philippe Roche

published 09 Mar 2010

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Identification of Small Molecule and Genetic Modulators of AON-Induced Dystrophin Exon Skipping by High-Throughput Screening

Debra A. O'Leary, Orzala Sharif, Paul Anderson, Buu Tu, Genevieve Welch, Yingyao Zhou, Jeremy S. Caldwell, Ingo H. Engels, Achim Brinker

published 17 Dec 2009

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Toward the Discovery of Vaccine Adjuvants: Coupling In Silico Screening and In Vitro Analysis of Antagonist Binding to Human and Mouse CCR4 Receptors

Matthew N. Davies, Jagadeesh Bayry, Elma Z. Tchilian, Janakiraman Vani, Melkote S. Shaila, Emily K. Forbes, Simon J. Draper, Peter C. L. Beverley, David F. Tough, Darren R. Flower

published 30 Nov 2009

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Tyrosine, Cysteine, and S-Adenosyl Methionine Stimulate In Vitro [FeFe] Hydrogenase Activation

Jon M. Kuchenreuther, James A. Stapleton, James R. Swartz

published 26 Oct 2009

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NSC23925, Identified in a High-Throughput Cell-Based Screen, Reverses Multidrug Resistance

Zhenfeng Duan, Edwin Choy, Francis J. Hornicek

published 12 Oct 2009

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The Small Molecule Inhibitor QLT0267 Radiosensitizes Squamous Cell Carcinoma Cells of the Head and Neck

Iris Eke, Franziska Leonhardt, Katja Storch, Stephanie Hehlgans, Nils Cordes

published 30 Jul 2009

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Identification and Characterization of Inhibitors of Human Apurinic/apyrimidinic Endonuclease APE1

Anton Simeonov, Avanti Kulkarni, Dorjbal Dorjsuren, Ajit Jadhav, Min Shen, Daniel R. McNeill, Christopher P. Austin, David M. Wilson III

published 01 Jun 2009

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MGL2⁺ Dermal Dendritic Cells Are Sufficient to Initiate Contact Hypersensitivity In Vivo

Yosuke Kumamoto, Kaori Denda-Nagai, Satoshi Aida, Nobuaki Higashi, Tatsuro Irimura

published 19 May 2009

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Dynamics of Uptake and Metabolism of Small Molecules in Cellular Response Systems

Maria Werner, Szabolcs Semsey, Kim Sneppen, Sandeep Krishna

published 17 Mar 2009

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Computer Aided Identification of Small Molecules Disrupting uPAR/α5β1- Integrin Interaction: A New Paradigm for Metastasis Prevention

Pratima Chaurasia, Mihaly Mezei, Ming-Ming Zhou, Liliana Ossowski

published 26 Feb 2009

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Discovery of a Novel Activator of KCNQ1-KCNE1 K⁺ Channel Complexes

Karen Mruk, William R. Kobertz

published 21 Jan 2009

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Small Molecule, Non-Peptide p75^NTR Ligands Inhibit Aβ-Induced Neurodegeneration and Synaptic Impairment

Tao Yang, Juliet K. Knowles, Qun Lu, Hong Zhang, Ottavio Arancio, Laura A. Moore, Timothy Chang, Qian Wang, Katrin Andreasson, Jayakumar Rajadas, Gerald G. Fuller, Youmei Xie, Stephen M. Massa, Frank M. Longo

published 03 Nov 2008

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