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Small molecules

Simultaneous Induction of Non-Canonical Autophagy and Apoptosis in Cancer Cells by ROS-Dependent ERK and JNK Activation

Chew Hooi Wong, Kartini Bte Iskandar, [ ... ], Shazib Pervaiz

Atomic Analysis of Protein-Protein Interfaces with Known Inhibitors: The 2P2I Database

Raphaël Bourgeas, Marie-Jeanne Basse, Xavier Morelli, Philippe Roche

Identification of Small Molecule and Genetic Modulators of AON-Induced Dystrophin Exon Skipping by High-Throughput Screening

Debra A. O'Leary, Orzala Sharif, [ ... ], Achim Brinker

Toward the Discovery of Vaccine Adjuvants: Coupling In Silico Screening and In Vitro Analysis of Antagonist Binding to Human and Mouse CCR4 Receptors

Matthew N. Davies, Jagadeesh Bayry, [ ... ], Darren R. Flower

Tyrosine, Cysteine, and S-Adenosyl Methionine Stimulate In Vitro [FeFe] Hydrogenase Activation

Jon M. Kuchenreuther, James A. Stapleton, James R. Swartz

NSC23925, Identified in a High-Throughput Cell-Based Screen, Reverses Multidrug Resistance

Zhenfeng Duan, Edwin Choy, Francis J. Hornicek

The Small Molecule Inhibitor QLT0267 Radiosensitizes Squamous Cell Carcinoma Cells of the Head and Neck

Iris Eke, Franziska Leonhardt, [ ... ], Nils Cordes

Identification and Characterization of Inhibitors of Human Apurinic/apyrimidinic Endonuclease APE1

Anton Simeonov, Avanti Kulkarni, [ ... ], David M. Wilson III

MGL2⁺ Dermal Dendritic Cells Are Sufficient to Initiate Contact Hypersensitivity In Vivo

Yosuke Kumamoto, Kaori Denda-Nagai, [ ... ], Tatsuro Irimura

Dynamics of Uptake and Metabolism of Small Molecules in Cellular Response Systems

Maria Werner, Szabolcs Semsey, Kim Sneppen, Sandeep Krishna

Computer Aided Identification of Small Molecules Disrupting uPAR/α5β1- Integrin Interaction: A New Paradigm for Metastasis Prevention

Pratima Chaurasia, Mihaly Mezei, Ming-Ming Zhou, Liliana Ossowski

Discovery of a Novel Activator of KCNQ1-KCNE1 K⁺ Channel Complexes

Karen Mruk, William R. Kobertz

Small Molecule, Non-Peptide p75^NTR Ligands Inhibit Aβ-Induced Neurodegeneration and Synaptic Impairment

Tao Yang, Juliet K. Knowles, [ ... ], Frank M. Longo

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