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Small molecules

Tyrosine Kinase Syk Non-Enzymatic Inhibitors and Potential Anti-Allergic Drug-Like Compounds Discovered by Virtual and In Vitro Screening

Bruno O. Villoutreix, Guillaume Laconde, David Lagorce, Pierre Martineau, Maria A. Miteva, Piona Dariavach

published 20 Jun 2011

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p53 Transactivation and the Impact of Mutations, Cofactors and Small Molecules Using a Simplified Yeast-Based Screening System

Virginia Andreotti, Yari Ciribilli, Paola Monti, Alessandra Bisio, Mattia Lion, Jennifer Jordan, Gilberto Fronza, Paola Menichini, Michael A. Resnick, Alberto Inga

published 02 Jun 2011

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Identification of Small-Molecule Inhibitors of Yersinia pestis Type III Secretion System YscN ATPase

Wieslaw Swietnicki, Daniel Carmany, Michael Retford, Mark Guelta, Russell Dorsey, Joel Bozue, Michael S. Lee, Mark A. Olson

published 18 May 2011

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Non-Conjugated Small Molecule FRET for Differentiating Monomers from Higher Molecular Weight Amyloid Beta Species

Chongzhao Ran, Wei Zhao, Robert D. Moir, Anna Moore

published 29 Apr 2011

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Small-Molecule Inhibitor Leads of Ribosome-Inactivating Proteins Developed Using the Doorstop Approach

Yuan-Ping Pang, Jewn Giew Park, Shaohua Wang, Anuradha Vummenthala, Rajesh K. Mishra, John E. McLaughlin, Rong Di, Jennifer Nielsen Kahn, Nilgun E. Tumer, Laszlo Janosi, Jon Davis, Charles B. Millard

published 24 Mar 2011

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Efficient Feeder-Free Episomal Reprogramming with Small Molecules

Junying Yu, Kevin Fongching Chau, Maxim A. Vodyanik, Jinlan Jiang, Yong Jiang

published 01 Mar 2011

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DNA Polymerase β as a Novel Target for Chemotherapeutic Intervention of Colorectal Cancer

Aruna S. Jaiswal, Sanjeev Banerjee, Ritu Aneja, Fazlul H. Sarkar, David A. Ostrov, Satya Narayan

published 02 Feb 2011

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Activation of Pluripotency Genes in Human Fibroblast Cells by a Novel mRNA Based Approach

Jordan R. Plews, JianLiang Li, Mark Jones, Harry D. Moore, Chris Mason, Peter W. Andrews, Jie Na

published 30 Dec 2010

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Homodimerization of the Death-Associated Protein Kinase Catalytic Domain: Development of a New Small Molecule Fluorescent Reporter

Michael Zimmermann, Cédric Atmanene, Qingyan Xu, Laetitia Fouillen, Alain Van Dorsselaer, Dominique Bonnet, Claire Marsol, Marcel Hibert, Sarah Sanglier-Cianferani, Claire Pigault, Laurie K. McNamara, D. Martin Watterson, Jacques Haiech, Marie-Claude Kilhoffer

published 30 Nov 2010

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Rift Valley Fever Virus Infection of Human Cells and Insect Hosts Is Promoted by Protein Kinase C Epsilon

Claire Marie Filone, Sheri L. Hanna, M. Cecilia Caino, Shelly Bambina, Robert W. Doms, Sara Cherry

published 24 Nov 2010

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A Stem Cell-Based Tool for Small Molecule Screening in Adipogenesis

Jie Qin, Wei-Qiang Li, Li Zhang, Fei Chen, Wen-Hua Liang, Frank Fuxiang Mao, Xiu-Ming Zhang, Bruce T. Lahn, Wei-Hua Yu, Andy Peng Xiang

published 27 Sep 2010

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Presaging Critical Residues in Protein interfaces-Web Server (PCRPi-W): A Web Server to Chart Hot Spots in Protein Interfaces

Joan Segura Mora, Salam A. Assi, Narcis Fernandez-Fuentes

published 23 Aug 2010

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Production of Native Bispecific Antibodies in Rabbits

Wei Wang, Ruihuan Xu, Jinming Li

published 14 Jun 2010

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