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Small molecules

Structure Based Discovery of Small Molecules to Regulate the Activity of Human Insulin Degrading Enzyme

Bilal Çakir, Onur Dağliyan, [ ... ], Metin Türkay

Identification of Anti-Malarial Compounds as Novel Antagonists to Chemokine Receptor CXCR4 in Pancreatic Cancer Cells

Joseph Kim, M. L. Richard Yip, [ ... ], Nagarajan Vaidehi

Activation and Inhibition of Transglutaminase 2 in Mice

Laila Dafik, Megan Albertelli, [ ... ], Chaitan Khosla

An Immunoassay for Dibutyl Phthalate Based on Direct Hapten Linkage to the Polystyrene Surface of Microtiter Plates

Chenxi Wei, Shumao Ding, [ ... ], Junlin Yuan

Novel Patient Cell-Based HTS Assay for Identification of Small Molecules for a Lysosomal Storage Disease

Haifeng Geng, Grace Whiteley, [ ... ], Gustavo H. B. Maegawa

Characterization of Pellicle Inhibition in Gluconacetobacter xylinus 53582 by a Small Molecule, Pellicin, Identified by a Chemical Genetics Screen

Janice L. Strap, Andrew Latos, Isaac Shim, Dario T. Bonetta

Discovery of Novel MDR-Mycobacterium tuberculosis Inhibitor by New FRIGATE Computational Screen

Christoph Scheich, Zoltán Szabadka, [ ... ], Markus Schade

Molecular Evolution of the Transmembrane Domains of G Protein-Coupled Receptors

Sarosh N. Fatakia, Stefano Costanzi, Carson C. Chow

Efficient Generation of Fully Reprogrammed Human iPS Cells via Polycistronic Retroviral Vector and a New Cocktail of Chemical Compounds

Zhonghui Zhang, Yongxing Gao, [ ... ], Wen-Shu Wu

Novel Allosteric Sites on Ras for Lead Generation

Barry J. Grant, Suryani Lukman, [ ... ], Alemayehu A. Gorfe

Xanthene Food Dye, as a Modulator of Alzheimer's Disease Amyloid-beta Peptide Aggregation and the Associated Impaired Neuronal Cell Function

H. Edward Wong, Inchan Kwon

Discovery of Diverse Small Molecule Chemotypes with Cell-Based PKD1 Inhibitory Activity

Elizabeth R. Sharlow, Gabriela Mustata Wilson, [ ... ], John S. Lazo

A Systems Approach for Tumor Pharmacokinetics

Greg Michael Thurber, Ralph Weissleder

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