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Small molecules

Novel Patient Cell-Based HTS Assay for Identification of Small Molecules for a Lysosomal Storage Disease

Haifeng Geng, Grace Whiteley, [ ... ], Gustavo H. B. Maegawa

Characterization of Pellicle Inhibition in Gluconacetobacter xylinus 53582 by a Small Molecule, Pellicin, Identified by a Chemical Genetics Screen

Janice L. Strap, Andrew Latos, Isaac Shim, Dario T. Bonetta

Discovery of Novel MDR-Mycobacterium tuberculosis Inhibitor by New FRIGATE Computational Screen

Christoph Scheich, Zoltán Szabadka, [ ... ], Markus Schade

Molecular Evolution of the Transmembrane Domains of G Protein-Coupled Receptors

Sarosh N. Fatakia, Stefano Costanzi, Carson C. Chow

Efficient Generation of Fully Reprogrammed Human iPS Cells via Polycistronic Retroviral Vector and a New Cocktail of Chemical Compounds

Zhonghui Zhang, Yongxing Gao, [ ... ], Wen-Shu Wu

Novel Allosteric Sites on Ras for Lead Generation

Barry J. Grant, Suryani Lukman, [ ... ], Alemayehu A. Gorfe

Xanthene Food Dye, as a Modulator of Alzheimer's Disease Amyloid-beta Peptide Aggregation and the Associated Impaired Neuronal Cell Function

H. Edward Wong, Inchan Kwon

Discovery of Diverse Small Molecule Chemotypes with Cell-Based PKD1 Inhibitory Activity

Elizabeth R. Sharlow, Gabriela Mustata Wilson, [ ... ], John S. Lazo

A Systems Approach for Tumor Pharmacokinetics

Greg Michael Thurber, Ralph Weissleder

Acute Drug Treatment in the Early C. elegans Embryo

Ana Carvalho, Sara K. Olson, [ ... ], Karen Oegema

High-Content Chemical and RNAi Screens for Suppressors of Neurotoxicity in a Huntington's Disease Model

Joost Schulte, Katharine J. Sepp, [ ... ], J. Troy Littleton

Efficient Non-Viral Reprogramming of Myoblasts to Stemness with a Single Small Molecule to Generate Cardiac Progenitor Cells

Zeeshan Pasha, Husnain Kh Haider, Muhammad Ashraf

Comprehensive Structural and Substrate Specificity Classification of the Saccharomyces cerevisiae Methyltransferome

Tomasz Wlodarski, Jan Kutner, [ ... ], Krzysztof Ginalski

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