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Small molecules

On the Mechanism of Action of SJ-172550 in Inhibiting the Interaction of MDM4 and p53

Michal Bista, David Smithson, Aleksandra Pecak, Gabriella Salinas, Katarzyna Pustelny, Jaeki Min, Artur Pirog, Kristin Finch, Michal Zdzalik, Brett Waddell, Benedykt Wladyka, Sylwia Kedracka-Krok, Michael A. Dyer, Grzegorz Dubin, R. Kiplin Guy

published 04 Jun 2012

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Immunogenicity of a Promiscuous T Cell Epitope Peptide Based Conjugate Vaccine against Benzo[a]pyrene: Redirecting Antibodies to the Hapten

Mario T. Schellenberger, Nathalie Grova, Sophie Farinelle, Stéphanie Willième, Dominique Revets, Claude P. Muller

published 30 May 2012

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In Silico Assessment of Potential Druggable Pockets on the Surface of α₁-Antitrypsin Conformers

Anathe O. M. Patschull, Bibek Gooptu, Paul Ashford, Tina Daviter, Irene Nobeli

published 08 May 2012

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High Throughput Screening for Small Molecule Enhancers of the Interferon Signaling Pathway to Drive Next-Generation Antiviral Drug Discovery

Dhara A. Patel, Anand C. Patel, William C. Nolan, Yong Zhang, Michael J. Holtzman

published 04 May 2012

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Identification and Characterization of Antifungal Compounds Using a Saccharomyces cerevisiae Reporter Bioassay

Brad Tebbets, Douglas Stewart, Stephanie Lawry, Jeniel Nett, Andre Nantel, David Andes, Bruce S. Klein

published 04 May 2012

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Differential Scanning Fluorometry Signatures as Indicators of Enzyme Inhibitor Mode of Action: Case Study of Glutathione S-Transferase

Wendy A. Lea, Anton Simeonov

published 30 Apr 2012

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A Chemocentric Approach to the Identification of Cancer Targets

Beáta Flachner, Zsolt Lörincz, Angelo Carotti, Orazio Nicolotti, Praveena Kuchipudi, Nikita Remez, Ferran Sanz, József Tóvári, Miklós J. Szabó, Béla Bertók, Sándor Cseh, Jordi Mestres, György Dormán

published 25 Apr 2012

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Modulation of GSK-3β Activity in Venezuelan Equine Encephalitis Virus Infection

Kylene Kehn-Hall, Aarthi Narayanan, Lindsay Lundberg, Gavin Sampey, Chelsea Pinkham, Irene Guendel, Rachel Van Duyne, Svetlana Senina, Kimberly L. Schultz, Eric Stavale, M. Javad Aman, Charles Bailey, Fatah Kashanchi

published 04 Apr 2012

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Highly Parallel Translation of DNA Sequences into Small Molecules

Rebecca M. Weisinger, S. Jarrett Wrenn, Pehr B. Harbury

published 29 Mar 2012

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Genital HSV-2 Infection Induces Short-Term NK Cell Memory

Mohamed F. Abdul-Careem, Amanda J. Lee, Elishka A. Pek, Navkiran Gill, Amy E. Gillgrass, Marianne V. Chew, Sarah Reid, Ali A. Ashkar

published 22 Mar 2012

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A Cell-Based Small Molecule Screening Method for Identifying Inhibitors of Epithelial-Mesenchymal Transition in Carcinoma

Kian-Ngiap Chua, Wen-Jing Sim, Victor Racine, Shi-Yun Lee, Boon Cher Goh, Jean Paul Thiery

published 14 Mar 2012

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Selection of Diethylstilbestrol-Specific Single-Chain Antibodies from a Non-Immunized Mouse Ribosome Display Library

Yanan Sun, Baoan Ning, Ming Liu, Xianjun Gao, Xianjun Fan, Jianqing Liu, Zhixian Gao

published 13 Mar 2012

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Text Mining Improves Prediction of Protein Functional Sites

Karin M. Verspoor, Judith D. Cohn, Komandur E. Ravikumar, Michael E. Wall

published 29 Feb 2012

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