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Small molecules

On the Mechanism of Action of SJ-172550 in Inhibiting the Interaction of MDM4 and p53

Michal Bista, David Smithson, [ ... ], R. Kiplin Guy

Immunogenicity of a Promiscuous T Cell Epitope Peptide Based Conjugate Vaccine against Benzo[a]pyrene: Redirecting Antibodies to the Hapten

Mario T. Schellenberger, Nathalie Grova, [ ... ], Claude P. Muller

In Silico Assessment of Potential Druggable Pockets on the Surface of α₁-Antitrypsin Conformers

Anathe O. M. Patschull, Bibek Gooptu, [ ... ], Irene Nobeli

High Throughput Screening for Small Molecule Enhancers of the Interferon Signaling Pathway to Drive Next-Generation Antiviral Drug Discovery

Dhara A. Patel, Anand C. Patel, [ ... ], Michael J. Holtzman

Identification and Characterization of Antifungal Compounds Using a Saccharomyces cerevisiae Reporter Bioassay

Brad Tebbets, Douglas Stewart, [ ... ], Bruce S. Klein

Differential Scanning Fluorometry Signatures as Indicators of Enzyme Inhibitor Mode of Action: Case Study of Glutathione S-Transferase

Wendy A. Lea, Anton Simeonov

A Chemocentric Approach to the Identification of Cancer Targets

Beáta Flachner, Zsolt Lörincz, [ ... ], György Dormán

Modulation of GSK-3β Activity in Venezuelan Equine Encephalitis Virus Infection

Kylene Kehn-Hall, Aarthi Narayanan, [ ... ], Fatah Kashanchi

Highly Parallel Translation of DNA Sequences into Small Molecules

Rebecca M. Weisinger, S. Jarrett Wrenn, Pehr B. Harbury

Genital HSV-2 Infection Induces Short-Term NK Cell Memory

Mohamed F. Abdul-Careem, Amanda J. Lee, [ ... ], Ali A. Ashkar

A Cell-Based Small Molecule Screening Method for Identifying Inhibitors of Epithelial-Mesenchymal Transition in Carcinoma

Kian-Ngiap Chua, Wen-Jing Sim, [ ... ], Jean Paul Thiery

Selection of Diethylstilbestrol-Specific Single-Chain Antibodies from a Non-Immunized Mouse Ribosome Display Library

Yanan Sun, Baoan Ning, [ ... ], Zhixian Gao

Text Mining Improves Prediction of Protein Functional Sites

Karin M. Verspoor, Judith D. Cohn, Komandur E. Ravikumar, Michael E. Wall

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