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Small molecules

Exposure to small molecule cocktails allows induction of neural crest lineage cells from human adipose-derived mesenchymal stem cells

Yuzo Takayama, Yuka Akagi, Yoichiro Shibuya, Yasuyuki S. Kida

Interaction between β-lactoglobulin and EGCG under high-pressure by molecular dynamics simulation

Yechuan Huang, Xicai Zhang, Huayi Suo

Effects of Small Molecule Calcium-Activated Chloride Channel Inhibitors on Structure and Function of Accessory Cholera Enterotoxin (Ace) of Vibrio cholerae

Tanaya Chatterjee, Irshad Ali Sheikh, [ ... ], Kazi Mirajul Hoque

Phosphatase Inhibitors Function as Novel, Broad Spectrum Botulinum Neurotoxin Antagonists in Mouse and Human Embryonic Stem Cell-Derived Motor Neuron-Based Assays

Erkan Kiris, Jonathan E. Nuss, [ ... ], Sina Bavari

Targeting mitochondrial DNA polymerase gamma for selective inhibition of MLH1 deficient colon cancer growth

Berna Somuncu, Aysegul Ekmekcioglu, [ ... ], Meltem Muftuoglu

Harnessing the biological complexity of Big Data from LINCS gene expression signatures

Aliyu Musa, Shailesh Tripathi, [ ... ], Frank Emmert-Streib

DNA-Dependent Protein Kinase Is a Context Dependent Regulator of Lmx1a and Midbrain Specification

Cameron P. Hunt, Stewart A. Fabb, Colin W. Pouton, John M. Haynes

IA-Lab: A MATLAB framework for efficient microscopy image analysis development, applied to quantifying intracellular transport of internalized peptide-drug conjugate

Adam M. Corrigan, Johan Karlsson, [ ... ], Yinhai Wang

Extracellular Regulated Kinase 1/2 Signaling Is a Critical Regulator of Interleukin-1β-Mediated Astrocyte Tissue Inhibitor of Metalloproteinase-1 Expression

Jerel Fields, Irma E. Cisneros, Kathleen Borgmann, Anuja Ghorpade

Improved Derivation Efficiency and Pluripotency of Stem Cells from the Refractory Inbred C57BL/6 Mouse Strain by Small Molecules

Chih-Jen Lin, Tomokazu Amano, Yong Tang, Xiuchun Tian

A novel small molecule LLL12B inhibits STAT3 signaling and sensitizes ovarian cancer cell to paclitaxel and cisplatin

Ruijie Zhang, Xiaozhi Yang, [ ... ], Jiayuh Lin

A Physiologically-Motivated Compartment-Based Model of the Effect of Inhaled Hypertonic Saline on Mucociliary Clearance and Liquid Transport in Cystic Fibrosis

Matthew R. Markovetz, Timothy E. Corcoran, [ ... ], Robert S. Parker

Small Molecule Screening with Laser Cytometry Can Be Used to Identify Pro-Survival Molecules in Human Embryonic Stem Cells

Sean P. Sherman, April D. Pyle

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