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Small molecules

Identification of small molecule agonists of fetal hemoglobin expression for the treatment of sickle cell disease

Jian-Ping Yang, Rachel Toughiri, [ ... ], Shane R. Horman

Probing of Exosites Leads to Novel Inhibitor Scaffolds of HCV NS3/4A Proteinase

Sergey A. Shiryaev, Anton V. Cheltsov, Alex Y. Strongin

A novel pre-clinical antibacterial pipeline database

Sarah Paulin, Richard A. Alm, Peter Beyer

Targeting Non-Small Cell Lung Cancer Cells by Dual Inhibition of the Insulin Receptor and the Insulin-Like Growth Factor-1 Receptor

Emma E. Vincent, Douglas J. E. Elder, [ ... ], Jeremy M. Tavaré

High content, high-throughput screening for small molecule inducers of NF-κB translocation

Samuel Njikan, Alyssa J. Manning, [ ... ], Tanya Parish

Small molecule inhibitor of tau self-association in a mouse model of tauopathy: A preventive study in P301L tau JNPL3 mice

Eliot J. Davidowitz, Patricia Lopez, [ ... ], James G. Moe

Interaction between β-lactoglobulin and EGCG under high-pressure by molecular dynamics simulation

Yechuan Huang, Xicai Zhang, Huayi Suo

A high-throughput screen identifies inhibitors of the interaction between the oncogenic transcription factor ERG and the cofactor EWS

Taylor R. Nicholas, Jingwei Meng, [ ... ], Peter C. Hollenhorst

Biophysical characterization of hit compounds for mechanism-based enzyme activation

Xiangying Guan, Alok Upadhyay, Sudipto Munshi, Raj Chakrabarti

Selection of Diethylstilbestrol-Specific Single-Chain Antibodies from a Non-Immunized Mouse Ribosome Display Library

Yanan Sun, Baoan Ning, [ ... ], Zhixian Gao

MMpI: A WideRange of Available Compounds of Matrix Metalloproteinase Inhibitors

Charuvaka Muvva, Sanjukta Patra, Subramanian Venkatesan

A Mechanistic Model of Early FcεRI Signaling: Lipid Rafts and the Question of Protection from Dephosphorylation

Dipak Barua, Byron Goldstein

Exposure to small molecule cocktails allows induction of neural crest lineage cells from human adipose-derived mesenchymal stem cells

Yuzo Takayama, Yuka Akagi, Yoichiro Shibuya, Yasuyuki S. Kida

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