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Small molecules

New Insights into [FeFe] Hydrogenase Activation and Maturase Function

Jon M. Kuchenreuther, R. David Britt, James R. Swartz

published 25 Sep 2012

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Predicting Metabolic Pathways of Small Molecules and Enzymes Based on Interaction Information of Chemicals and Proteins

Yu-Fei Gao, Lei Chen, Yu-Dong Cai, Kai-Yan Feng, Tao Huang, Yang Jiang

published 21 Sep 2012

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High-Throughput 1,536-Well Fluorescence Polarization Assays for α₁-Acid Glycoprotein and Human Serum Albumin Binding

Adam Yasgar, Silviya D. Furdas, David J. Maloney, Ajit Jadhav, Manfred Jung, Anton Simeonov

published 20 Sep 2012

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A Targeted Library Screen Reveals a New Inhibitor Scaffold for Protein Kinase D

Manuj Tandon, Lirong Wang, Qi Xu, Xiangqun Xie, Peter Wipf, Qiming Jane Wang

published 18 Sep 2012

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Direct Chromatin PCR (DC-PCR): Hypotonic Conditions Allow Differentiation of Chromatin States during Thermal Cycling

Sergei Vatolin, Shahper N. Khan, Frederic J. Reu

published 12 Sep 2012

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Intracellular Context Affects Levels of a Chemically Dependent Destabilizing Domain

Mark A. Sellmyer, Ling-chun Chen, Emily L. Egeler, Rishi Rakhit, Thomas J. Wandless

published 12 Sep 2012

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Characterization of Isoenzyme-Selective Inhibitors of Human Sphingosine Kinases

Peng Gao, Yuri K. Peterson, Ryan A. Smith, Charles D. Smith

published 10 Sep 2012

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Differential Activities of the Two Closely Related Withanolides, Withaferin A and Withanone: Bioinformatics and Experimental Evidences

Kirti Vaishnavi, Nishant Saxena, Navjot Shah, Rumani Singh, Kavyashree Manjunath, M. Uthayakumar, Shankar P. Kanaujia, Sunil C. Kaul, Kanagaraj Sekar, Renu Wadhwa

published 04 Sep 2012

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Screen Anti-influenza Lead Compounds That Target the PA_C Subunit of H5N1 Viral RNA Polymerase

Lin Li, Shenghai Chang, Junfeng Xiang, Qian Li, Huanhuan Liang, Yalin Tang, Yingfang Liu

published 24 Aug 2012

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CD8+ T Cell Migration to the Skin Requires CD4+ Help in a Murine Model of Contact Hypersensitivity

Nanna Fyhrquist, Henrik Wolff, Antti Lauerma, Harri Alenius

published 20 Aug 2012

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A Small Molecule Agonist of EphA2 Receptor Tyrosine Kinase Inhibits Tumor Cell Migration In Vitro and Prostate Cancer Metastasis In Vivo

Aaron Petty, Eugene Myshkin, Haina Qin, Hong Guo, Hui Miao, Gregory P. Tochtrop, Jer-Tsong Hsieh, Phillip Page, Lili Liu, Daniel J. Lindner, Chayan Acharya, Alexander D. MacKerell Jr, Eckhard Ficker, Jianxing Song, Bingcheng Wang

published 15 Aug 2012

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Anti-Tumor Activity of a Novel HS-Mimetic-Vascular Endothelial Growth Factor Binding Small Molecule

Basappa , Kazuyuki Sugahara, Kuntebommanahalli N. Thimmaiah, Hemant K. Bid, Peter J. Houghton, Kanchugarakoppal S. Rangappa

published 15 Aug 2012

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Curcumin Prevents Formation of Polyglutamine Aggregates by Inhibiting Vps36, a Component of the ESCRT-II Complex

Meenakshi Verma, Abhishek Sharma, Swarna Naidu, Ankan Kumar Bhadra, Ritushree Kukreti, Vibha Taneja

published 07 Aug 2012

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