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Small molecules

Small Molecule Screening with Laser Cytometry Can Be Used to Identify Pro-Survival Molecules in Human Embryonic Stem Cells

Sean P. Sherman, April D. Pyle

published 29 Jan 2013

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Wrapping Effects within a Proposed Function-Rescue Strategy for the Y220C Oncogenic Mutation of Protein p53

Sebastián R. Accordino, J. Ariel Rodríguez Fris, Gustavo A. Appignanesi

published 24 Jan 2013

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Stability of Zinc Finger Nuclease Protein Is Enhanced by the Proteasome Inhibitor MG132

Suresh Ramakrishna, Young-Hoon Kim, Hyongbum Kim

published 24 Jan 2013

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Identification of a Small Molecule That Modifies MglA/SspA Interaction and Impairs Intramacrophage Survival of Francisella tularensis

Algevis P. Wrench, Christopher L. Gardner, Claudio F. Gonzalez, Graciela L. Lorca

published 23 Jan 2013

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TAZ Expression as a Prognostic Indicator in Colorectal Cancer

Hiu-Fung Yuen, Cian M. McCrudden, Yu-Han Huang, Jill M. Tham, Xiaoqian Zhang, Qi Zeng, Shu-Dong Zhang, WanJin Hong

published 23 Jan 2013

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Development of an Enzyme Linked Immunosorbent Assay and an Immunochromatographic Assay for Detection of Organophosphorus Pesticides in Different Agricultural Products

Xiude Hua, Jifei Yang, Limin Wang, Qingkui Fang, Gaiping Zhang, Fengquan Liu

published 31 Dec 2012

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Cell Surface Concentrations and Concentration Ranges for Testing In Vitro Autocrine Loops and Small Molecules

Nikhil Mittal

published 28 Dec 2012

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Global Effect of Inauhzin on Human p53-Responsive Transcriptome

Jun-Ming Liao, Shelya X. Zeng, Xiang Zhou, Hua Lu

published 21 Dec 2012

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A Mechanistic Model of Early FcεRI Signaling: Lipid Rafts and the Question of Protection from Dephosphorylation

Dipak Barua, Byron Goldstein

published 17 Dec 2012

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Hexachlorophene Is a Potent KCNQ1/KCNE1 Potassium Channel Activator Which Rescues LQTs Mutants

Yueming Zheng, Xuejing Zhu, Pingzheng Zhou, Xi Lan, Haiyan Xu, Min Li, Zhaobing Gao

published 12 Dec 2012

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What Can We Learn from the Evolution of Protein-Ligand Interactions to Aid the Design of New Therapeutics?

Alicia P. Higueruelo, Adrian Schreyer, G. Richard J Bickerton, Tom L. Blundell, Will R. Pitt

published 11 Dec 2012

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Crystal Structure of Two Anti-Porphyrin Antibodies with Peroxidase Activity

Victor Muñoz Robles, Jean-Didier Maréchal, Amel Bahloul, Marie-Agnès Sari, Jean-Pierre Mahy, Béatrice Golinelli-Pimpaneau

published 11 Dec 2012

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Using RosettaLigand for Small Molecule Docking into Comparative Models

Kristian W. Kaufmann, Jens Meiler

published 11 Dec 2012

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