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Small molecules

Effect of Currently Approved Carriers and Adjuvants on the Pre-Clinical Efficacy of a Conjugate Vaccine against Oxycodone in Mice and Rats

Marco Pravetoni, Jeffrey S. Vervacke, [ ... ], Paul R. Pentel

Chemokine Receptor CXCR7 Is a Functional Receptor for CXCL12 in Brain Endothelial Cells

Yang Liu, Eleanor Carson-Walter, Kevin A. Walter

DNA repair and replication links to pluripotency and differentiation capacity of pig iPS cells

Kai Liu, Jian Mao, [ ... ], Lin Liu

Anti-Tumor Activity of a Novel HS-Mimetic-Vascular Endothelial Growth Factor Binding Small Molecule

Basappa , Kazuyuki Sugahara, [ ... ], Kanchugarakoppal S. Rangappa

A Panel of Diverse Assays to Interrogate the Interaction between Glucokinase and Glucokinase Regulatory Protein, Two Vital Proteins in Human Disease

Matthew G. Rees, Mindy I. Davis, [ ... ], Anton Simeonov

CD8+ T Cell Migration to the Skin Requires CD4+ Help in a Murine Model of Contact Hypersensitivity

Nanna Fyhrquist, Henrik Wolff, Antti Lauerma, Harri Alenius

Discovery of Small-Molecule Modulators of the Human Y₄ Receptor

Gregory Sliwoski, Mario Schubert, [ ... ], Jens Meiler

Composition of Overlapping Protein-Protein and Protein-Ligand Interfaces

Ruzianisra Mohamed, Jennifer Degac, Volkhard Helms

Structure-activity studies of Mdm2/Mdm4-binding stapled peptides comprising non-natural amino acids

Sharon Min Qi Chee, Jantana Wongsantichon, [ ... ], Farid J. Ghadessy

A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models

Natalia J. Martinez, Ganesha Rai, [ ... ], Anton Simeonov

A Natural-Like Synthetic Small Molecule Impairs Bcr-Abl Signaling Cascades and Induces Megakaryocyte Differentiation in Erythroleukemia Cells

Silvia Turroni, Manlio Tolomeo, [ ... ], Maurizio Recanatini

Discovery of a potent, selective, and tumor-suppressing antibody antagonist of adenosine A_2A receptor

Linya Wang, Pankaj Garg, [ ... ], Aaron K. Sato

Dynamics of Uptake and Metabolism of Small Molecules in Cellular Response Systems

Maria Werner, Szabolcs Semsey, Kim Sneppen, Sandeep Krishna

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