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Small molecules

Development of a Specific Monoclonal Antibody-Based ELISA to Measure the Artemether Content of Antimalarial Drugs

Suqin Guo, Yongliang Cui, [ ... ], Liwang Cui

Efficacy of Cyclin Dependent Kinase 4 Inhibitors as Potent Neuroprotective Agents against Insults Relevant to Alzheimer’s Disease

Priyankar Sanphui, Sumit Kumar Pramanik, [ ... ], Subhas Chandra Biswas

Development of a Fluorescence Polarization Based High-Throughput Assay to Identify Casitas B-Lineage Lymphoma RING Domain Regulators

Xingliang Xie, Lin Sun, [ ... ], Yiyi Sun

Substrate and Inhibitor Specificity of the Type II p21-Activated Kinase, PAK6

Jia Gao, Byung Hak Ha, [ ... ], Titus J. Boggon

DNA-Dependent Protein Kinase Is a Context Dependent Regulator of Lmx1a and Midbrain Specification

Cameron P. Hunt, Stewart A. Fabb, Colin W. Pouton, John M. Haynes

Inhibition of Influenza H7 Hemagglutinin-Mediated Entry

Aleksandar Antanasijevic, Han Cheng, [ ... ], Michael Caffrey

Discovery and Computer Aided Potency Optimization of a Novel Class of Small Molecule CXCR4 Antagonists

Victoria Vinader, Djevdet S. Ahmet, [ ... ], Kamyar Afarinkia

Electrostatic Similarities between Protein and Small Molecule Ligands Facilitate the Design of Protein-Protein Interaction Inhibitors

Arnout Voet, Francois Berenger, Kam Y. J. Zhang

High-Throughput Screening (HTS) and Hit Validation to Identify Small Molecule Inhibitors with Activity against NS3/4A proteases from Multiple Hepatitis C Virus Genotypes

Hyun Lee, Tian Zhu, [ ... ], Michael E. Johnson

Sulfamethoxazole Induces a Switch Mechanism in T Cell Receptors Containing TCRVβ20-1, Altering pHLA Recognition

Stephan Watkins, Werner J. Pichler

Selection of a Novel Anti-Nicotine Vaccine: Influence of Antigen Design on Antibody Function in Mice

David C. Pryde, Lyn H. Jones, [ ... ], Michael J. McCluskie

Ligand Pose and Orientational Sampling in Molecular Docking

Ryan G. Coleman, Michael Carchia, [ ... ], Brian K. Shoichet

The Relationship between Functional Inhibition and Binding for K_Ca2 Channel Blockers

David Charles Hammond Benton, Monique Garbarg, Guy William John Moss

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