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Small molecules

Simultaneous Inhibition of the HGF/MET and Erk1/2 Pathways Affect Uveal Melanoma Cell Growth and Migration

Chandrani Chattopadhyay, Elizabeth A. Grimm, Scott E. Woodman

Automated NMR Fragment Based Screening Identified a Novel Interface Blocker to the LARG/RhoA Complex

Jia Gao, Rongsheng Ma, [ ... ], Ke Ruan

A Monoclonal Antibody TrkB Receptor Agonist as a Potential Therapeutic for Huntington’s Disease

Daniel Todd, Ian Gowers, [ ... ], Jonathan A. Bard

Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site

Young Do Kwon, Judith M. LaLonde, [ ... ], Peter D. Kwong

In Vitro and In Vivo Activity of a Novel Antifungal Small Molecule against Candida Infections

Sarah Sze Wah Wong, Richard Yi Tsun Kao, [ ... ], Chaminda Jayampath Seneviratne

Chronic Treatment with Novel Small Molecule Hsp90 Inhibitors Rescues Striatal Dopamine Levels but Not α-Synuclein-Induced Neuronal Cell Loss

Nikolaus R. McFarland, Hemi Dimant, [ ... ], Pamela J. McLean

Efficient and Rapid Induction of Human iPSCs/ESCs into Nephrogenic Intermediate Mesoderm Using Small Molecule-Based Differentiation Methods

Toshikazu Araoka, Shin-ichi Mae, [ ... ], Kenji Osafune

Elevated Peptides in Lung Lavage Fluid Associated with Bronchiolitis Obliterans Syndrome

Matthew D. Stone, Stephen B. Harvey, [ ... ], Chris H. Wendt

Substantial Conformational Change Mediated by Charge-Triad Residues of the Death Effector Domain in Protein-Protein Interactions

Edward C. Twomey, Dana F. Cordasco, Stephen D. Kozuch, Yufeng Wei

Inhibition of DNA Glycosylases via Small Molecule Purine Analogs

Aaron C. Jacobs, Marcus J. Calkins, [ ... ], R. Stephen Lloyd

A Fluorescence-Based Thermal Shift Assay Identifies Inhibitors of Mitogen Activated Protein Kinase Kinase 4

Sankar N. Krishna, Chi-Hao Luan, [ ... ], Raymond C. Bergan

Small Molecule Proprotein Convertase Inhibitors for Inhibition of Embryo Implantation

Huiting Ho, Harmeet Singh, [ ... ], Guiying Nie

Multiplex Cytological Profiling Assay to Measure Diverse Cellular States

Sigrun M. Gustafsdottir, Vebjorn Ljosa, [ ... ], Alykhan F. Shamji

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