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Small molecules

A High Throughput Screening Assay System for the Identification of Small Molecule Inhibitors of gsp

Nisan Bhattacharyya, Xin Hu, [ ... ], Michael T. Collins

Convallatoxin, a Dual Inducer of Autophagy and Apoptosis, Inhibits Angiogenesis In Vitro and In Vivo

Seung Ya Yang, Nam Hee Kim, [ ... ], Ho Jeong Kwon

Multimodal Effects of Small Molecule ROCK and LIMK Inhibitors on Mitosis, and Their Implication as Anti-Leukemia Agents

Yusuke Oku, Chiaki Tareyanagi, [ ... ], Yoshimasa Uehara

Pharmacological Inhibition of TPL2/MAP3K8 Blocks Human Cytotoxic T Lymphocyte Effector Functions

Fatema Z. Chowdhury, Leonardo D. Estrada, [ ... ], J. David Farrar

Inhibition of TGFβ Signaling Increases Direct Conversion of Fibroblasts to Induced Cardiomyocytes

Jamie L. Ifkovits, Russell C. Addis, Jonathan A. Epstein, John D. Gearhart

Small Molecule Inhibitors Target the Tissue Transglutaminase and Fibronectin Interaction

Bakhtiyor Yakubov, Lan Chen, [ ... ], Daniela Matei

A Panel of Diverse Assays to Interrogate the Interaction between Glucokinase and Glucokinase Regulatory Protein, Two Vital Proteins in Human Disease

Matthew G. Rees, Mindy I. Davis, [ ... ], Anton Simeonov

Identification and Characterization of Sebaceous Gland Atrophy-Sparing DGAT1 Inhibitors

Eric S. Muise, Yonghua Zhu, [ ... ], Shirly Pinto

Role of Molecular Charge in Nucleocytoplasmic Transport

Alexander Goryaynov, Weidong Yang

Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein by Small Molecules as a Potential Therapeutic Strategy for Parkinson’s Disease

Gergely Tóth, Shyra J. Gardai, [ ... ], Lisa McConlogue

Simultaneous Inhibition of the HGF/MET and Erk1/2 Pathways Affect Uveal Melanoma Cell Growth and Migration

Chandrani Chattopadhyay, Elizabeth A. Grimm, Scott E. Woodman

Automated NMR Fragment Based Screening Identified a Novel Interface Blocker to the LARG/RhoA Complex

Jia Gao, Rongsheng Ma, [ ... ], Ke Ruan

A Monoclonal Antibody TrkB Receptor Agonist as a Potential Therapeutic for Huntington’s Disease

Daniel Todd, Ian Gowers, [ ... ], Jonathan A. Bard

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