Advertisement

Browse Subject Areas

?

Click through the PLOS taxonomy to find articles in your field.

For more information about PLOS Subject Areas, click here.

Small molecules

Simultaneous Measurement of Smoothened Entry Into and Exit From the Primary Cilium

Jynho Kim, Elaine Y. C. Hsia, James Kim, Navdar Sever, Philip A. Beachy, Xiaoyan Zheng

published 13 Aug 2014

Loading metrics information...

Metrics unavailable. Please check back later.

Structure of a Stapled Peptide Antagonist Bound to Nutlin-Resistant Mdm2

Sharon Min Qi Chee, Jantana Wongsantichon, Quah Soo Tng, Robert Robinson, Thomas L. Joseph, Chandra Verma, David P. Lane, Christopher J. Brown, Farid J. Ghadessy

published 12 Aug 2014

Loading metrics information...

Metrics unavailable. Please check back later.

A High-Throughput Assay for Small Molecule Destabilizers of the KRAS Oncoprotein

Joseph Carver, Thomas S. Dexheimer, Dennis Hsu, Meng-Tzu Weng, Jordan L. Smith, Rajarshi Guha, Ajit Jadhav, Anton Simeonov, Ji Luo

published 05 Aug 2014

Loading metrics information...

Metrics unavailable. Please check back later.

Chemokine Receptor CXCR7 Is a Functional Receptor for CXCL12 in Brain Endothelial Cells

Yang Liu, Eleanor Carson-Walter, Kevin A. Walter

published 01 Aug 2014

Loading metrics information...

Metrics unavailable. Please check back later.

Imine Resveratrol Analogues: Molecular Design, Nrf2 Activation and SAR Analysis

Chang Li, Xiaofei Xu, Xiu Jun Wang, Yuanjiang Pan

published 16 Jul 2014

Loading metrics information...

Metrics unavailable. Please check back later.

A Small Molecule Inhibitor of Human RAD51 Potentiates Breast Cancer Cell Killing by Therapeutic Agents in Mouse Xenografts

Fei Huang, Alexander V. Mazin

published 27 Jun 2014

Loading metrics information...

Metrics unavailable. Please check back later.

Pharmacological Validation of an Inward-Rectifier Potassium (Kir) Channel as an Insecticide Target in the Yellow Fever Mosquito Aedes aegypti

Matthew F. Rouhier, Rene Raphemot, Jerod S. Denton, Peter M. Piermarini

published 24 Jun 2014

Loading metrics information...

Metrics unavailable. Please check back later.

The Human Orphan Nuclear Receptor Tailless (TLX, NR2E1) Is Druggable

Cindy Benod, Rosa Villagomez, Carly S. Filgueira, Peter K. Hwang, Paul G. Leonard, Guillaume Poncet-Montange, Senapathy Rajagopalan, Robert J. Fletterick, Jan-Åke Gustafsson, Paul Webb

published 17 Jun 2014

Loading metrics information...

Metrics unavailable. Please check back later.

Investigating the Dynamic Aspects of Drug-Protein Recognition through a Combination of MD and NMR Analyses: Implications for the Development of Protein-Protein Interaction Inhibitors

Massimiliano Meli, Katiuscia Pagano, Laura Ragona, Giorgio Colombo

published 27 May 2014

Loading metrics information...

Metrics unavailable. Please check back later.

Targeting of the MYCN Protein with Small Molecule c-MYC Inhibitors

Inga Müller, Karin Larsson, Anna Frenzel, Ganna Oliynyk, Hanna Zirath, Edward V. Prochownik, Nicholas J. Westwood, Marie Arsenian Henriksson

published 23 May 2014

Loading metrics information...

Metrics unavailable. Please check back later.

Effect of ENaC Modulators on Rat Neural Responses to NaCl

Shobha Mummalaneni, Jie Qian, Tam-Hao T. Phan, Mee-Ra Rhyu, Gerard L. Heck, John A. DeSimone, Vijay Lyall

published 19 May 2014

Loading metrics information...

Metrics unavailable. Please check back later.

A Novel TetR-Regulating Peptide Turns off rtTA-Mediated Activation of Gene Expression

Sebastian Schmidt, Christian Berens, Marcus Klotzsche

published 08 May 2014

Loading metrics information...

Metrics unavailable. Please check back later.

Effect of Currently Approved Carriers and Adjuvants on the Pre-Clinical Efficacy of a Conjugate Vaccine against Oxycodone in Mice and Rats

Marco Pravetoni, Jeffrey S. Vervacke, Mark D. Distefano, Ashli M. Tucker, Megan Laudenbach, Paul R. Pentel

published 05 May 2014

Loading metrics information...

Metrics unavailable. Please check back later.

Advertisement

Create a weekly email alert for: Small molecules

You can change these options by clicking profile then "Alerts and Notifications"