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Small molecules

Highly Parallel Translation of DNA Sequences into Small Molecules

Rebecca M. Weisinger, S. Jarrett Wrenn, Pehr B. Harbury

Structure- and Ligand-Based Virtual Screening Identifies New Scaffolds for Inhibitors of the Oncoprotein MDM2

Douglas R. Houston, Li-Hsuan Yen, Simon Pettit, Malcolm D. Walkinshaw

BDNF, NT-3 and Trk receptor agonist monoclonal antibodies promote neuron survival, neurite extension, and synapse restoration in rat cochlea ex vivo models relevant for hidden hearing loss

Stephanie Szobota, Pranav D. Mathur, [ ... ], Alan C. Foster

New Approaches of PARP-1 Inhibitors in Human Lung Cancer Cells and Cancer Stem-Like Cells by Some Selected Anthraquinone-Derived Small Molecules

Yu-Ru Lee, Dah-Shyong Yu, [ ... ], Hsu-Shan Huang

Comparative biophysical characterization: A screening tool for acetylcholinesterase inhibitors

Devashree N. Patil, Sushama A. Patil, Srinivas Sistla, Jyoti P. Jadhav

A receptor tyrosine kinase ROR1 inhibitor (KAN0439834) induced significant apoptosis of pancreatic cells which was enhanced by erlotinib and ibrutinib

Amir Hossein Daneshmanesh, Mohammad Hojjat-Farsangi, [ ... ], Håkan Mellstedt

Glucagon-Like Peptide-1 Receptor Ligand Interactions: Structural Cross Talk between Ligands and the Extracellular Domain

Graham M. West, Francis S. Willard, [ ... ], Patrick R. Griffin

Energetics of Transport through the Nuclear Pore Complex

Ali Ghavami, Erik van der Giessen, Patrick R. Onck

On the Mechanism of Action of SJ-172550 in Inhibiting the Interaction of MDM4 and p53

Michal Bista, David Smithson, [ ... ], R. Kiplin Guy

FDA orphan drug designations for lysosomal storage disorders – a cross-sectional analysis

Sven F. Garbade, Matthias Zielonka, [ ... ], Markus Ries

Small Molecule Inhibitors Target the Tissue Transglutaminase and Fibronectin Interaction

Bakhtiyor Yakubov, Lan Chen, [ ... ], Daniela Matei

Live-Cell Microscopy Reveals Small Molecule Inhibitor Effects on MAPK Pathway Dynamics

Daniel J. Anderson, Jenni K. Durieux, [ ... ], Mary J. C. Ludlam

Integrated Bio-Entity Network: A System for Biological Knowledge Discovery

Lindsey Bell, Rajesh Chowdhary, [ ... ], Jinfeng Zhang

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