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Small molecules

A High-Throughput Small Molecule Screen for C. elegans Linker Cell Death Inhibitors

Andrew R. Schwendeman, Shai Shaham

published 07 Oct 2016

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Computational Analysis and Predictive Cheminformatics Modeling of Small Molecule Inhibitors of Epigenetic Modifiers

Salma Jamal, Sonam Arora, Vinod Scaria

published 13 Sep 2016

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Small Molecule-Induced Complement Factor D (Adipsin) Promotes Lipid Accumulation and Adipocyte Differentiation

No-Joon Song, Suji Kim, Byung-Hyun Jang, Seo-Hyuk Chang, Ui Jeong Yun, Ki-Moon Park, Hironori Waki, Dean Y. Li, Peter Tontonoz, Kye Won Park

published 09 Sep 2016

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A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models

Natalia J. Martinez, Ganesha Rai, Adam Yasgar, Wendy A. Lea, Hongmao Sun, Yuhong Wang, Diane K. Luci, Shyh-Ming Yang, Kana Nishihara, Shunichi Takeda, Mohiuddin Sagor, Irina Earnshaw, Tetsuya Okada, Kazutoshi Mori, Kelli Wilson, Gregory J. Riggins, Menghang Xia, Maurizio Grimaldi, Ajit Jadhav, David J. Maloney, Anton Simeonov

published 29 Aug 2016

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MMpI: A WideRange of Available Compounds of Matrix Metalloproteinase Inhibitors

Charuvaka Muvva, Sanjukta Patra, Subramanian Venkatesan

published 10 Aug 2016

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Epidermal Neuromedin U Attenuates IgE-Mediated Allergic Skin Inflammation

Yoshiko Mizukawa, Takaaki Doi, Yoshimi Yamazaki, Akihiko Kudo, Tetsuo Shiohara

published 27 Jul 2016

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A Sensitive and Robust High-Throughput Screening Assay for Inhibitors of the Chikungunya Virus nsP1 Capping Enzyme

Kristen M. Bullard-Feibelman, Benjamin P. Fuller, Brian J. Geiss

published 18 Jul 2016

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Identification, Functional Characterization and Regulon Prediction of a Novel Two Component System Comprising BAS0540-BAS0541 of Bacillus anthracis

Monisha Gopalani, Alisha Dhiman, Amit Rahi, Divya Kandari, Rakesh Bhatnagar

published 08 Jul 2016

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Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function

Calvin H. Yeh, Alan R. Stafford, Beverly A. Leslie, James C. Fredenburgh, Jeffrey I. Weitz

published 15 Jun 2016

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Discovery of Small-Molecule Modulators of the Human Y₄ Receptor

Gregory Sliwoski, Mario Schubert, Jan Stichel, David Weaver, Annette G. Beck-Sickinger, Jens Meiler

published 13 Jun 2016

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Biochemical Preparation of Cell Extract for Cell-Free Protein Synthesis without Physical Disruption

Kei Fujiwara, Nobuhide Doi

published 29 Apr 2016

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Molecular Characterisation of Small Molecule Agonists Effect on the Human Glucagon Like Peptide-1 Receptor Internalisation

Aiysha Thompson, Jeffrey W. Stephens, Stephen C. Bain, Venkateswarlu Kanamarlapudi

published 21 Apr 2016

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BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic β-Cell

Jude T. Deeney, Anna C. Belkina, Orian S. Shirihai, Barbara E. Corkey, Gerald V. Denis

published 23 Mar 2016

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