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Small molecules

Epidermal Neuromedin U Attenuates IgE-Mediated Allergic Skin Inflammation

Yoshiko Mizukawa, Takaaki Doi, [ ... ], Tetsuo Shiohara

A Sensitive and Robust High-Throughput Screening Assay for Inhibitors of the Chikungunya Virus nsP1 Capping Enzyme

Kristen M. Bullard-Feibelman, Benjamin P. Fuller, Brian J. Geiss

Identification, Functional Characterization and Regulon Prediction of a Novel Two Component System Comprising BAS0540-BAS0541 of Bacillus anthracis

Monisha Gopalani, Alisha Dhiman, [ ... ], Rakesh Bhatnagar

Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function

Calvin H. Yeh, Alan R. Stafford, [ ... ], Jeffrey I. Weitz

Discovery of Small-Molecule Modulators of the Human Y₄ Receptor

Gregory Sliwoski, Mario Schubert, [ ... ], Jens Meiler

Biochemical Preparation of Cell Extract for Cell-Free Protein Synthesis without Physical Disruption

Kei Fujiwara, Nobuhide Doi

Molecular Characterisation of Small Molecule Agonists Effect on the Human Glucagon Like Peptide-1 Receptor Internalisation

Aiysha Thompson, Jeffrey W. Stephens, Stephen C. Bain, Venkateswarlu Kanamarlapudi

BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic β-Cell

Jude T. Deeney, Anna C. Belkina, [ ... ], Gerald V. Denis

Energetic Landscape of MDM2-p53 Interactions by Computational Mutagenesis of the MDM2-p53 Interaction

Kelly M. Thayer, George A. Beyer

GPU-Accelerated Molecular Dynamics Simulation to Study Liquid Crystal Phase Transition Using Coarse-Grained Gay-Berne Anisotropic Potential

Wenduo Chen, Youliang Zhu, [ ... ], Yunqi Li

NK Cells Respond to Haptens by the Activation of Calcium Permeable Plasma Membrane Channels

Camille Grandclément, Horst Pick, Horst Vogel, Werner Held

A New Application of Parallel Synthesis Strategy for Discovery of Amide-Linked Small Molecules as Potent Chondroprotective Agents in TNF-α-Stimulated Chondrocytes

Chia-Chung Lee, Yang Lo, [ ... ], Hsu-Shan Huang

Zinc Chloride Transiently Maintains Mouse Embryonic Stem Cell Pluripotency by Activating Stat3 Signaling

Jing Hu, Zhiyong Yang, [ ... ], Jiajing Cheng

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