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Small molecules

Uncovering the molecular and physiological processes of anticancer leads binding human serum albumin: A physical insight into drug efficacy

Chuanbo Liu, Zuojia Liu, Jin Wang

Comparison of cell-based assays for the identification and evaluation of competitive CXCR4 inhibitors

Anneleen Van Hout, Thomas D’huys, [ ... ], Tom Van Loy

The prognostic significance of DAPK1 in bladder cancer

Jian-Yun Xie, Peng-Chen Chen, [ ... ], Yao Lin

Non-invasive phenotyping and drug testing in single cardiomyocytes or beta-cells by calcium imaging and optogenetics

Yu-Fen Chang, Connor N. Broyles, [ ... ], Matthew J. Daniels

DNA repair and replication links to pluripotency and differentiation capacity of pig iPS cells

Kai Liu, Jian Mao, [ ... ], Lin Liu

The scoring bias in reverse docking and the score normalization strategy to improve success rate of target fishing

Qiyao Luo, Liang Zhao, [ ... ], Liangren Zhang

Effective antibodies immobilization and functionalized nanoparticles in a quartz-crystal microbalance-based immunosensor for the detection of parathion

Bartolomeo Della Ventura, Marco Iannaccone, [ ... ], Raffaele Velotta

Large-scale bioactivity analysis of the small-molecule assayed proteome

Tyler William H. Backman, Daniel S. Evans, Thomas Girke

A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity

Adam Yasgar, Steven A. Titus, [ ... ], Natalia J. Martinez

Systems Based Study of the Therapeutic Potential of Small Charged Molecules for the Inhibition of IL-1 Mediated Cartilage Degradation

Saptarshi Kar, David W. Smith, Bruce S. Gardiner, Alan J. Grodzinsky

A ^99mTc-Labelled Tetrazine for Bioorthogonal Chemistry. Synthesis and Biodistribution Studies with Small Molecule trans-Cyclooctene Derivatives

Alyssa Vito, Hussain Alarabi, [ ... ], John F. Valliant

Identification of a Novel Inhibitory Allosteric Site in p38α

Patricia Gomez-Gutierrez, Pedro M. Campos, Miguel Vega, Juan J. Perez

Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics

W. Joon Chung, Jennifer L. Goeckeler-Fried, [ ... ], Eric J. Sorscher

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