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Small molecules

Derivation and Expansion Using Only Small Molecules of Human Neural Progenitors for Neurodegenerative Disease Modeling

Peter Reinhardt, Michael Glatza, [ ... ], Jared Sterneckert

A high-throughput screen to identify novel small molecule inhibitors of the Werner Syndrome Helicase-Nuclease (WRN)

Joshua A. Sommers, Tomasz Kulikowicz, [ ... ], Robert M. Brosh Jr.

Multiplex Cytological Profiling Assay to Measure Diverse Cellular States

Sigrun M. Gustafsdottir, Vebjorn Ljosa, [ ... ], Alykhan F. Shamji

A Molecular Mechanism for Direct Sirtuin Activation by Resveratrol

Melanie Gertz, Giang Thi Tuyet Nguyen, [ ... ], Clemens Steegborn

Dorsomorphin, a Selective Small Molecule Inhibitor of BMP Signaling, Promotes Cardiomyogenesis in Embryonic Stem Cells

Jijun Hao, Marie A. Daleo, [ ... ], Charles C. Hong

Promotion of Prescription Drugs to Consumers and Providers, 2001–2010

Rachel Kornfield, Julie Donohue, Ernst R. Berndt, G. Caleb Alexander

Ligand Pose and Orientational Sampling in Molecular Docking

Ryan G. Coleman, Michael Carchia, [ ... ], Brian K. Shoichet

Benchmarking and Analysis of Protein Docking Performance in Rosetta v3.2

Sidhartha Chaudhury, Monica Berrondo, [ ... ], Jeffrey J. Gray

Efficient Feeder-Free Episomal Reprogramming with Small Molecules

Junying Yu, Kevin Fongching Chau, [ ... ], Yong Jiang

Sortase Enzyme-Mediated Generation of Site-Specifically Conjugated Antibody Drug Conjugates with High In Vitro and In Vivo Potency

Roger R. Beerli, Tamara Hell, Anna S. Merkel, Ulf Grawunder

A Fluorescence-Based Thermal Shift Assay Identifies Inhibitors of Mitogen Activated Protein Kinase Kinase 4

Sankar N. Krishna, Chi-Hao Luan, [ ... ], Raymond C. Bergan

Timelines of translational science: From technology initiation to FDA approval

Laura M. McNamee, Michael Jay Walsh, Fred D. Ledley

Simultaneous Induction of Non-Canonical Autophagy and Apoptosis in Cancer Cells by ROS-Dependent ERK and JNK Activation

Chew Hooi Wong, Kartini Bte Iskandar, [ ... ], Shazib Pervaiz

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