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Small molecules

Derivation and Expansion Using Only Small Molecules of Human Neural Progenitors for Neurodegenerative Disease Modeling

Peter Reinhardt, Michael Glatza, [ ... ], Jared Sterneckert

A high-throughput screen to identify novel small molecule inhibitors of the Werner Syndrome Helicase-Nuclease (WRN)

Joshua A. Sommers, Tomasz Kulikowicz, [ ... ], Robert M. Brosh Jr.

Multiplex Cytological Profiling Assay to Measure Diverse Cellular States

Sigrun M. Gustafsdottir, Vebjorn Ljosa, [ ... ], Alykhan F. Shamji

Dorsomorphin, a Selective Small Molecule Inhibitor of BMP Signaling, Promotes Cardiomyogenesis in Embryonic Stem Cells

Jijun Hao, Marie A. Daleo, [ ... ], Charles C. Hong

Promotion of Prescription Drugs to Consumers and Providers, 2001–2010

Rachel Kornfield, Julie Donohue, Ernst R. Berndt, G. Caleb Alexander

A Molecular Mechanism for Direct Sirtuin Activation by Resveratrol

Melanie Gertz, Giang Thi Tuyet Nguyen, [ ... ], Clemens Steegborn

Ligand Pose and Orientational Sampling in Molecular Docking

Ryan G. Coleman, Michael Carchia, [ ... ], Brian K. Shoichet

Benchmarking and Analysis of Protein Docking Performance in Rosetta v3.2

Sidhartha Chaudhury, Monica Berrondo, [ ... ], Jeffrey J. Gray

Efficient Feeder-Free Episomal Reprogramming with Small Molecules

Junying Yu, Kevin Fongching Chau, [ ... ], Yong Jiang

A Fluorescence-Based Thermal Shift Assay Identifies Inhibitors of Mitogen Activated Protein Kinase Kinase 4

Sankar N. Krishna, Chi-Hao Luan, [ ... ], Raymond C. Bergan

Sortase Enzyme-Mediated Generation of Site-Specifically Conjugated Antibody Drug Conjugates with High In Vitro and In Vivo Potency

Roger R. Beerli, Tamara Hell, Anna S. Merkel, Ulf Grawunder

Simultaneous Induction of Non-Canonical Autophagy and Apoptosis in Cancer Cells by ROS-Dependent ERK and JNK Activation

Chew Hooi Wong, Kartini Bte Iskandar, [ ... ], Shazib Pervaiz

Timelines of translational science: From technology initiation to FDA approval

Laura M. McNamee, Michael Jay Walsh, Fred D. Ledley

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