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Small interfering RNA

A chemically optimized, GalNAc-conjugated siRNA targeting HSD17B13 demonstrates efficacy in a human 3D organoid model of MASH, showcasing an alternative to animal testing

Qin Meng, Xujia Wang, Yuxuan Zhang, Sudeep Pushpakom, Jun Yang, Hui Feng, Mu Wang

published 14 Aug 2026

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Induction of osteogenic differentiation of MSCs by GSK3β knockdown through GSK3β siRNAs transfection

Elena V. Galitsyna, Anastasiia A. Buianova, Tatiana B. Bukharova, Irina A. Krivosheeva, Mikhail Yu. Skoblov, Dmitriy V. Goldshtein

published 07 Aug 2026

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Long noncoding RNA Gpr137b-ps mediates 15-PGDH-induced angiogenesis in brain microvasculature following tMCAO in mice

Di Wang, Guojian Zhang, Haiyan Gou, Yawei Wang, Wenye Liang, Yangyue Cao, Yujuan Jiao

published 24 Jul 2026

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TBX20 promotes doxorubicin resistance in breast cancer cells through enhanced ABCC1 expression and inhibition of mitophagy

Shuai Nie, Dejian Liu, Jun Hu, Yu Gan, Liangliang Mi

published 17 Jul 2026

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Isoginkgetin increases the expression of metal responsive transcripts but inhibits their translation

Claire Peneycad, Erin van Zyl, Abhinav Mohur, Bruce C. McKay

published 25 Jun 2026

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Functional comparison of SP6 RNA polymerase and T7 RNA polymerase

Julia Gutbrod, Svenja Hehn, Antonia Bangnowski, Eleanor Fritz, Andreas Marx

published 22 Jun 2026

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Decreased expression of Ly-1 antibody reactive clone (Lyar) triggers enhanced adipogenesis of bone marrow mesenchymal stromal cells in aged bone marrow

Yu Shinyashiki, Yuta Onodera, Yusuke Kawashima, Natsumi Iwawaki, Toshiyuki Takehara, Koji Goto, Takeshi Teramura

published 27 May 2026

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Differential epigenetic regulation of glucose-induced alteration of miR-9 in retinal and cardiac endothelial cells

Eric Wang, Biao Feng, Shali Chen, Subrata Chakrabarti

published 21 May 2026

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Identification of CAND1 as a DNA-dependent protein kinase-regulated coactivator of androgen receptor and the ARv7 splice variant

Ross A. Hamilton, Basil Paul, Ping Yi, Kimal Rajapakshe, Anil K. Panigrahi, Sandra L. Grimm, Cristian Coarfa, Anna Malovannaya, Nancy L. Weigel, David M. Lonard, Charles E. Foulds

published 14 May 2026

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Fatty acid-binding protein 5 (FABP5) modulates limbal epithelial cell homeostasis by regulating the expression of key genes under both normal and inflammatory conditions, in vitro

Maryam Amini, Shao-Lun Hsu, Tanja Stachon, Zhen Li, Ning Chai, Fabian N. Fries, Berthold Seitz, Swarnali Kundu, Shweta Suiwal, Nóra Szentmáry

published 28 Apr 2026

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The role of SPP1 in evaluating the prognosis, immune infiltration, and drug sensitivity of hepatocellular carcinoma

Kai Cui, Xia Li, Yongrun Li, Zhong Li, Du Wang, Xinhong Wang, Shuxin Qin, Junjie Li, Jiaye Long

published 22 Apr 2026

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Overexpression generates aberrant distribution of endocytic regulators - the case of the Rab11/LAMP1 compartment

Sarah Hornfeck, Evgeniya Trofimenko, Christian Widmann

published 22 Apr 2026

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Down-regulation of circ0001361 induces apoptosis and suppresses the progression of glioma

Xiaoqiong Zou, Ping Wang, Weixia Nong, Chang Liu, Feng Li, Chunhong Xue, Xin Li, Yanjing Wang, Yingying Ge, Qingmei Zhang, Bin Luo, Xiaoxun Xie

published 15 Apr 2026

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