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Small interfering RNA

Chemigenetic Ca²⁺ indicators report elevated Ca²⁺ levels in endothelial Weibel-Palade bodies

Julian Terglane, Nicole Mertes, Sarah Weischer, Thomas Zobel, Kai Johnsson, Volker Gerke

published 27 Jan 2025

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Preliminary screening of new biomarkers for sepsis using bioinformatics and experimental validation

Hao Wang, Wei Xiong, Wu Zhong, Yingchun Hu

published 24 Jan 2025

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Reduction of Cystatin B results in increased cathepsin B activity in disomic but not Trisomy 21 human cellular and mouse models

Yixing Wu, Karen Cleverley, Frances K. Wiseman

published 22 Jan 2025

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Calcium phosphate formation and deposition in ischemic neurons

Shu Q. Liu, John B. Troy, Jeremy Goldman, Roger J. Guillory

published 16 Jan 2025

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Chlorogenic acid inhibits NLRP3 inflammasome activation through Nrf2 activation in diabetic nephropathy

Liping Bao, Yuhan Gong, Wenji Xu, Jun Dao, Jinjin Rao, Haihui Yang

published 06 Jan 2025

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The MIR-NAT MAPT-AS1 does not regulate Tau expression in human neurons

Rafaela Policarpo, Leen Wolfs, Saul Martínez-Montero, Lina Vandermeulen, Ines Royaux, Gert Van Peer, Pieter Mestdagh, Bart De Strooper, Annerieke Sierksma, Constantin d’Ydewalle

published 06 Jan 2025

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miRNA-328-3p regulates ZO-1 expression and inhibits PEDV proliferation via the PLC-β1-PKC pathway

Han Zhao, Jiayu Zhang, Dengliang Li, Zhanding Cui, Jiuyuan Liu, Di Bao, Yiming Wei, Xinyue Zhang, Zhimin Wu, Tianqi Zhang, Kai Wang, Shushuai Yi, Wei Lian, Guixue Hu

published 03 Jan 2025

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High glucose promotes macrophage switching to the M1 phenotype via the downregulation of STAT-3 mediated autophagy

Yu Zhao, Yuteng Jiang, Fengmei Wang, Li Sun, Mengyuan Ding, Liyuan Zhang, Beibei Wu, Xiaoliang Zhang

published 31 Dec 2024

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Matrix metalloproteinase-12 by M2 macrophages induced epithelial to mesenchymal transition in chronic rhinosinusitis with nasal polyps

Joo-Hoo Park, Jae-Min Shin, Hyun-Woo Yang, Tae Hoon Kim, Seung Hoon Lee, Ok Sarah Shin, Il-Ho Park

published 31 Dec 2024

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Loss of Mfn1 but not Mfn2 enhances adipogenesis

Jake P. Mann, Luis Carlos Tábara, Satish Patel, Pushpa Pushpa, Anna Alvarez-Guaita, Liang Dong, Afreen Haider, Koini Lim, Panna Tandon, Fabio Scurria, James E. N. Minchin, Stephen O’Rahilly S., Daniel J. Fazakerley, Julien Prudent, Robert K. Semple, David B. Savage

published 31 Dec 2024

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CAPE activates AMPK and Foxo3 signaling to induce growth inhibition and ferroptosis in triple-negative breast cancer

Qilu Fang, Qichuan Fang, Rui Cheng, Tingting Feng, Wenxiu Xin

published 27 Dec 2024

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IRX-related homeobox gene MKX is a novel oncogene in acute myeloid leukemia

Stefan Nagel, Corinna Meyer, Claudia Pommerenke

published 17 Dec 2024

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HuD regulates apoptosis in N2a cells by regulating Msi2 expression

Naina Gaikwad, Rucha Sarwade, Sourav Halder, Gaurav Agarwal, Vasudevan Seshadri

published 16 Dec 2024

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