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Small interfering RNA

CAPE activates AMPK and Foxo3 signaling to induce growth inhibition and ferroptosis in triple-negative breast cancer

Qilu Fang, Qichuan Fang, Rui Cheng, Tingting Feng, Wenxiu Xin

published 27 Dec 2024

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IRX-related homeobox gene MKX is a novel oncogene in acute myeloid leukemia

Stefan Nagel, Corinna Meyer, Claudia Pommerenke

published 17 Dec 2024

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HuD regulates apoptosis in N2a cells by regulating Msi2 expression

Naina Gaikwad, Rucha Sarwade, Sourav Halder, Gaurav Agarwal, Vasudevan Seshadri

published 16 Dec 2024

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Enhancing lobaplatin sensitivity in lung adenocarcinoma through inhibiting LDHA-targeted metabolic pathways

Siyu Yuan, Wenjie Ou, Xuguang Mi, Junjie Hou

published 16 Dec 2024

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Comprehensive analysis of bioinformatics and system biology reveals the association between Girdin and hepatocellular carcinoma

Tengda Huang, Hongying Chen, Hongyuan Pan, Tian Wu, Xiangyi Ren, Liwen Qin, Kefei Yuan, Fang He

published 13 Dec 2024

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Identification of druggable targets from the interactome of the Androgen Receptor and Serum Response Factor pathways in prostate cancer

Haleema Azam, Colin Veale, Kim Zitzmann, Simone Marcone, William M. Gallagher, Maria Prencipe

published 13 Dec 2024

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Neuron-associated retroelement-derived protein Arc/Arg3.1 assists in the early stages of alphaherpesvirus infection in human neuronal cells

Hiroko Kobayashi, Mitsuki Yasukochi, Masayuki Horie, Yasuko Orba, Hirofumi Sawa, Kan Fujino, Satoshi Taharaguchi

published 12 Dec 2024

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THUMPD3 regulates alternative splicing of ECM transcripts in human lung cancer cells and promotes proliferation and migration

Marie Klimontova, Han Zhang, Francisco Campos-Laborie, Natalie Webster, Byron Andrews, Kimberley Chung Kim Chung, Ryan Hili, Tony Kouzarides, Andrew J. Bannister

published 10 Dec 2024

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Enhanced bacteriostasis and osseointegrative properties of SiRNA-modified polyetheretherketone surface for implant applications

Zhen Liu, Libin Yang, Yazhuo Ni, Keying Chen, Qiquan Yan, Zhiying Zhao, Bo Xu, Yaoyang Li, Rui Li, Jianwen Li

published 05 Dec 2024

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GLP-1RA improves diabetic renal injury by alleviating glomerular endothelial cells pyrotosis via RXRα/circ8411/miR-23a-5p/ABCA1 pathway

Weixi Wu, Yao Wang, Xian Shao, Shuai Huang, Jian Wang, Saijun Zhou, Hongyan Liu, Yao Lin, Pei Yu

published 02 Dec 2024

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The NF-κB-HE4 axis: A novel regulator of HE4 secretion in ovarian cancer

Kyukwang Kim, Negar Khazan, Jamie L. McDowell, Cameron W. A. Snyder, John P. Miller, Rakesh K. Singh, Michelle E. Whittum, Rachael Turner, Richard G. Moore

published 02 Dec 2024

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Anti-necroptotic effects of human Wharton’s jelly-derived mesenchymal stem cells in skeletal muscle cell death model via secretion of GRO-α

Sang Eon Park, Soo Jin Kwon, Sun Jeong Kim, Jang Bin Jeong, Min-Jeong Kim, Suk-joo Choi, Soo-young Oh, Gyu Ha Ryu, Hong Bae Jeon, Jong Wook Chang

published 02 Dec 2024

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REST-dependent glioma progression occurs independently of the repression of the long non-coding RNA HAR1A

Ella Waters, Perla Pucci, Ruman Rahman, Anna P. Yatsyshyna, Harry Porter, Mark Hirst, Radka Gromnicova, Igor Kraev, Vera Mongiardini, Benedetto Grimaldi, Jon Golding, Helen L. Fillmore, Balázs Győrffy, Priyadarsini Gangadharannambiar, Christos N. Velanis, Christopher J. Heath, Francesco Crea

published 27 Nov 2024

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