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Small interfering RNA

Lipo-PGE1 suppresses collagen production in human dermal fibroblasts via the ERK/Ets-1 signaling pathway

Yoolhee Yang, Hee Jung Kim, Kyong-Je Woo, Daeho Cho, Sa Ik Bang

published 23 Jun 2017

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Epidermal growth factor promotes cyclin G2 degradation via calpain-mediated proteolysis in gynaecological cancer cells

Stefanie Bernaudo, Shahin Khazai, Eilyad Honarparvar, Alina Kopteva, Chun Peng

published 22 Jun 2017

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Novel siRNA formulation to effectively knockdown mutant p53 in osteosarcoma

Anup K. Kundu, Swathi V. Iyer, Sruti Chandra, Amit S. Adhikari, Tomoo Iwakuma, Tarun K. Mandal

published 21 Jun 2017

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Small molecule inhibitors uncover synthetic genetic interactions of human flap endonuclease 1 (FEN1) with DNA damage response genes

Thomas A. Ward, Peter J. McHugh, Stephen T. Durant

published 19 Jun 2017

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Regulation of type 1 iodothyronine deiodinase by LXRα

Yoriko Sakane, Naotetsu Kanamoto, Ichiro Yamauchi, Tetsuya Tagami, Yusuke Morita, Masako Miura, Masakatsu Sone, Akihiro Yasoda, Takeshi Kimura, Kazuwa Nakao, Nobuya Inagaki

published 15 Jun 2017

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Molecular cloning, characterization and expression analysis of Frizzled 6 in the small intestine of pigs (Sus scrofa)

Lijun Zou, Xiaocheng Wang, Liping Jiang, Shengping Wang, Xia Xiong, Huansheng Yang, Wei Gao, Min Gong, Chien-An A. Hu, Yulong Yin

published 14 Jun 2017

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Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1α and VEGF receptors

Nadine Mahfouz, Roula Tahtouh, Nada Alaaeddine, Joelle El Hajj, Riad Sarkis, Ray Hachem, Issam Raad, George Hilal

published 08 Jun 2017

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Candidate genes on murine chromosome 8 are associated with susceptibility to Staphylococcus aureus infection in mice and are involved with Staphylococcus aureus septicemia in humans

Qin Yan, Sun Hee Ahn, Felix Mba Medie, Batu K. Sharma-Kuinkel, Lawrence P. Park, William K. Scott, Hitesh Deshmukh, Ephraim L. Tsalik, Derek D. Cyr, Christopher W. Woods, Chen-Hsin Albert Yu, Carlton Adams, Robert Qi, Brenda Hansen, Vance G. Fowler Jr

published 08 Jun 2017

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SUMO regulates p21^Cip1 intracellular distribution and with p21^Cip1 facilitates multiprotein complex formation in the nucleolus upon DNA damage

Sonia Brun, Neus Abella, Maria T. Berciano, Olga Tapia, Montserrat Jaumot, Raimundo Freire, Miguel Lafarga, Neus Agell

published 05 Jun 2017

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Enhanced expression and phosphorylation of Sirt7 activates smad2 and ERK signaling and promotes the cardiac fibrosis differentiation upon angiotensin-II stimulation

Haichen Wang, Shengwu Liu, Shengqiang Liu, Wei Wei, Xiaolong Zhou, Fang Lin, Juanjuan Wang, Jinye Chen, Guodong Zhang, Yongbing Pang

published 05 Jun 2017

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Action of YM155 on clear cell renal cell carcinoma does not depend on survivin expression levels

Mei Yi Sim, Hung Huynh, Mei Lin Go, John Shyi Peng Yuen

published 05 Jun 2017

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Mxi1-0 regulates the growth of human umbilical vein endothelial cells through extracellular signal-regulated kinase 1/2 (ERK1/2) and interleukin-8 (IL-8)-dependent pathways

Weiling Wu, Zhenzhen Hu, Feng Wang, Hao Gu, Xiuqin Jiang, Jinjin Xu, Xi Zhan, Datong Zheng, Zhengdong Zhang

published 02 Jun 2017

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A RNAi-based therapeutic proof of concept targets salmonid whirling disease in vivo

Subhodeep Sarker, Simon Menanteau-Ledouble, Mohamed H. Kotob, Mansour El-Matbouli

published 02 Jun 2017

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