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Small interfering RNA

Long noncoding RNAs are dynamically regulated during β-cell mass expansion in mouse pregnancy and control β-cell proliferation in vitro

Giorgia Sisino, Alex-Xianghua Zhou, Niklas Dahr, Alan Sabirsh, Mangala M. Soundarapandian, Ranjan Perera, Erik Larsson-Lekholm, Maria Chiara Magnone, Magnus Althage, Björn Tyrberg

published 10 Aug 2017

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The quinic acid derivative KZ-41 prevents glucose-induced caspase-3 activation in retinal endothelial cells through an IGF-1 receptor dependent mechanism

Hui He, Rebecca L. Weir, Jordan J. Toutounchian, Jayaprakash Pagadala, Jena J. Steinle, Jerome Baudry, Duane D. Miller, Charles R. Yates

published 10 Aug 2017

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The long noncoding RNA XIAP-AS1 promotes XIAP transcription by XIAP-AS1 interacting with Sp1 in gastric cancer cells

Jun Cai, Dong Wang, Zhi-Gang Bai, Jie Yin, Jun Zhang, Zhong-Tao Zhang

published 08 Aug 2017

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Alteration of Wnt5a expression and of the non-canonical Wnt/PCP and Wnt/PKC-Ca²⁺ pathways in human osteoarthritis osteoblasts

Xavier Martineau, Élie Abed, Johanne Martel-Pelletier, Jean-Pierre Pelletier, Daniel Lajeunesse

published 04 Aug 2017

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Characterization of the genome of a phylogenetically distinct tospovirus and its interactions with the local lesion-induced host Chenopodium quinoa by whole-transcriptome analyses

Wan-Chen Chou, Shih-Shun Lin, Shyi-Dong Yeh, Siang-Ling Li, Ying-Che Peng, Ya-Hsu Fan, Tsung-Chi Chen

published 03 Aug 2017

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IL-25-induced activation of nasal fibroblast and its association with the remodeling of chronic rhinosinusitis with nasal polyposis

Soo-Kyoung Park, Yong-De Jin, Yeong-Kyu Park, Sun-Hee Yeon, Jun Xu, Rui-Ning Han, Ki-Sang Rha, Yong-Min Kim

published 03 Aug 2017

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Irisin regulates cardiac physiology in zebrafish

Lakshminarasimhan Sundarrajan, Chanel Yeung, Logan Hahn, Lynn P. Weber, Suraj Unniappan

published 03 Aug 2017

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Histone deacetylase inhibition prevents cell death induced by loss of tricellular tight junction proteins in temperature-sensitive mouse cochlear cells

Kenichi Takano, Takuya Kakuki, Yakuto Kaneko, Takayuki Kohno, Shin Kikuchi, Tetsuo Himi, Takashi Kojima

published 02 Aug 2017

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Insulin receptor signaling and glucagon-like peptide 1 effects on pancreatic beta cells

Nunzia Caporarello, Cristina Parrino, Vincenzo Trischitta, Lucia Frittitta

published 02 Aug 2017

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RORγt and RORα signature genes in human Th17 cells

Glenda Castro, Xuejun Liu, Karen Ngo, Aimee De Leon-Tabaldo, Shanrong Zhao, Rosa Luna-Roman, Jingxue Yu, Tinghua Cao, Robert Kuhn, Patrick Wilkinson, Krystal Herman, Marina I. Nelen, Jonathan Blevitt, Xiaohua Xue, Anne Fourie, Wai-Ping Fung-Leung

published 01 Aug 2017

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G protein-coupled receptor kinase 2 promotes cardiac hypertrophy

Philipp Schlegel, Julia Reinkober, Eric Meinhardt, Henrike Tscheschner, Erhe Gao, Sarah M. Schumacher, Ancai Yuan, Johannes Backs, Patrick Most, Thomas Wieland, Walter J. Koch, Hugo A. Katus, Philip W. Raake

published 31 Jul 2017

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Low doses of cholera toxin and its mediator cAMP induce CTLA-2 secretion by dendritic cells to enhance regulatory T cell conversion

Cinthia Silva-Vilches, Katrien Pletinckx, Miriam Lohnert, Vladimir Pavlovic, Diyaaeldin Ashour, Vini John, Emilia Vendelova, Susanne Kneitz, Jie Zhou, Rena Chen, Thomas Reinheckel, Thomas D. Mueller, Jochen Bodem, Manfred B. Lutz

published 31 Jul 2017

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Target specificity, in vivo pharmacokinetics, and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma

Peter Y. Yu, Heather L. Gardner, Ryan Roberts, Hakan Cam, Seethalakshmi Hariharan, Ling Ren, Amy K. LeBlanc, Hui Xiao, Jiayuh Lin, Denis C. Guttridge, Xiaokui Mo, Chad E. Bennett, Christopher C. Coss, Yonghua Ling, Mitch A. Phelps, Peter Houghton, Cheryl A. London

published 27 Jul 2017

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