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Small interfering RNA

Co-ordinated activation of classical and novel PKC isoforms is required for PMA-induced mTORC1 activation

Mengling Liu, Christopher J. Clarke, Mohamed F. Salama, Yeon Ja Choi, Lina M. Obeid, Yusuf A. Hannun

published 19 Sep 2017

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PI3K-C2α knockdown decreases autophagy and maturation of endocytic vesicles

Nathan M. Merrill, Joshua L. Schipper, Jonathan B. Karnes, Audra L. Kauffman, Katie R. Martin, Jeffrey P. MacKeigan

published 14 Sep 2017

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DUSP5 and DUSP6, two ERK specific phosphatases, are markers of a higher MAPK signaling activation in BRAF mutated thyroid cancers

Camille Buffet, Karine Hecale-Perlemoine, Léopoldine Bricaire, Florent Dumont, Camille Baudry, Frédérique Tissier, Jérôme Bertherat, Beatrix Cochand-Priollet, Marie-Laure Raffin-Sanson, Françoise Cormier, Lionel Groussin

published 14 Sep 2017

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Transgelin-2 is upregulated on activated B-cells and expressed in hyperplastic follicles in lupus erythematosus patients

Kaori Kiso, Hajime Yoshifuji, Takuma Oku, Masaki Hikida, Koji Kitagori, Yoshitaka Hirayama, Toshiki Nakajima, Hironori Haga, Tatsuaki Tsuruyama, Aya Miyagawa-Hayashino

published 14 Sep 2017

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Cyclic stretch induced IL-33 production through HMGB1/TLR-4 signaling pathway in murine respiratory epithelial cells

Jing Chang, Yuefeng Xia, Karla Wasserloos, Meihong Deng, Kory J. Blose, David A. Vorp, Heth R. Turnquist, Timothy R. Billiar, Bruce A. Pitt, Ma-Zhong Zhang, Li-Ming Zhang

published 12 Sep 2017

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Sigma 1 receptor regulates ERK activation and promotes survival of optic nerve head astrocytes

Jing Zhao, Barbara A. Mysona, Jing Wang, Graydon B. Gonsalvez, Sylvia B. Smith, Kathryn E. Bollinger

published 12 Sep 2017

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Androgen receptor-mediated downregulation of microRNA-221 and -222 in castration-resistant prostate cancer

Bin Gui, Chen-Lin Hsieh, Philip W. Kantoff, Adam S. Kibel, Li Jia

published 08 Sep 2017

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LAG-3 potentiates the survival of Mycobacterium tuberculosis in host phagocytes by modulating mitochondrial signaling in an in-vitro granuloma model

Bonnie L. Phillips, Uma S. Gautam, Allison N. Bucsan, Taylor W. Foreman, Nadia A. Golden, Tianhua Niu, Deepak Kaushal, Smriti Mehra

published 07 Sep 2017

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c-FLIP and the NOXA/Mcl-1 axis participate in the synergistic effect of pemetrexed plus cisplatin in human choroidal melanoma cells

Xiaofei Zhao, Feng Kong, Lei Wang, Han Zhang

published 01 Sep 2017

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Down-regulation of C35 decreased the cell viability and migration of breast ductal carcinoma cells

Wen Che, Yun Bao, Feng Tang

published 31 Aug 2017

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Phosphorylation of STAT3 at Tyr705 regulates MMP-9 production in epithelial ovarian cancer

Zan-Hui Jia, Yan Jia, Feng-Jun Guo, Jun Chen, Xi-Wen Zhang, Man-Hua Cui

published 31 Aug 2017

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Endoglin inhibition leads to intussusceptive angiogenesis via activation of factors related to COUP-TFII signaling pathway

Ruslan Hlushchuk, Beata Styp-Rekowska, Jehona Dzambazi, Monika Wnuk, Uyen Huynh-Do, Andrew Makanya, Valentin Djonov

published 31 Aug 2017

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Distinct roles and differential expression levels of Wnt5a mRNA isoforms in colorectal cancer cells

Tsui-Chin Huang, Pin-Tse Lee, Ming-Heng Wu, Chi-Chen Huang, Chiung-Yuan Ko, Yi-Chao Lee, Ding-Yen Lin, Ya-Wen Cheng, Kuen-Haur Lee

published 31 Aug 2017

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