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Small interfering RNA

Depletion of Kinesin 5B Affects Lysosomal Distribution and Stability and Induces Peri-Nuclear Accumulation of Autophagosomes in Cancer Cells

Carla M. P. Cardoso, Line Groth-Pedersen, Maria Høyer-Hansen, Thomas Kirkegaard, Elizabeth Corcelle, Jens S. Andersen, Marja Jäättelä, Jesper Nylandsted

published 10 Feb 2009

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HDAC3 as a Molecular Chaperone for Shuttling Phosphorylated TR2 to PML: A Novel Deacetylase Activity-Independent Function of HDAC3

Pawan Gupta, Ping-Chih Ho, Sung Gil Ha, Yi-Wei Lin, Li-Na Wei

published 10 Feb 2009

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Activation of DNA-PK by Ionizing Radiation Is Mediated by Protein Phosphatase 6

Jun Mi, Jaroslaw Dziegielewski, Elzbieta Bolesta, David L. Brautigan, James M. Larner

published 09 Feb 2009

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Deletion of the Mitochondrial Flavoprotein Apoptosis Inducing Factor (AIF) Induces β-Cell Apoptosis and Impairs β-Cell Mass

Fabienne T. Schulthess, Sophie Katz, Amin Ardestani, Hiroshi Kawahira, Senta Georgia, Domenico Bosco, Anil Bhushan, Kathrin Maedler

published 06 Feb 2009

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Ser276 Phosphorylation of NF-kB p65 by MSK1 Controls SCF Expression in Inflammation

Laurent Reber, Linda Vermeulen, Guy Haegeman, Nelly Frossard

published 06 Feb 2009

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Tensin3 Is a Negative Regulator of Cell Migration and All Four Tensin Family Members Are Downregulated in Human Kidney Cancer

Danuta Martuszewska, Börje Ljungberg, Martin Johansson, Göran Landberg, Cecilia Oslakovic, Björn Dahlbäck, Sassan Hafizi

published 04 Feb 2009

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Expression of Activated PIK3CA in Ovarian Surface Epithelium Results in Hyperplasia but Not Tumor Formation

Shun Liang, Nuo Yang, Yue Pan, Shan Deng, Xiaojuan Lin, Xiaojun Yang, Dionyssios Katsaros, Katherine F. Roby, Thomas C. Hamilton, Denise C. Connolly, George Coukos, Lin Zhang

published 27 Jan 2009

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The Internally Truncated LRP5 Receptor Presents a Therapeutic Target in Breast Cancer

Peyman Björklund, Jessica Svedlund, Anna-Karin Olsson, Göran Åkerström, Gunnar Westin

published 22 Jan 2009

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Septins Regulate Bacterial Entry into Host Cells

Serge Mostowy, To Nam Tham, Anne Danckaert, Stéphanie Guadagnini, Stéphanie Boisson-Dupuis, Javier Pizarro-Cerdá, Pascale Cossart

published 15 Jan 2009

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PGC-1α Is a Key Regulator of Glucose-Induced Proliferation and Migration in Vascular Smooth Muscle Cells

Lingyun Zhu, Guoxun Sun, Hongjie Zhang, Yan Zhang, Xi Chen, Xiaohong Jiang, Xueyuan Jiang, Stefan Krauss, Junfeng Zhang, Yang Xiang, Chen-Yu Zhang

published 14 Jan 2009

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Effective Treatment of Respiratory Alphaherpesvirus Infection Using RNA Interference

Amy Fulton, Sarah T. Peters, Gillian A. Perkins, Keith W. Jarosinski, Armando Damiani, Margaret Brosnahan, Elizabeth L. Buckles, Nikolaus Osterrieder, Gerlinde R. Van de Walle

published 05 Jan 2009

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Metal A and Metal B Sites of Nuclear RNA Polymerases Pol IV and Pol V Are Required for siRNA-Dependent DNA Methylation and Gene Silencing

Jeremy R. Haag, Olga Pontes, Craig S. Pikaard

published 01 Jan 2009

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An Epididymis-Specific Secretory Protein HongrES1 Critically Regulates Sperm Capacitation and Male Fertility

Yuchuan Zhou, Min Zheng, Qixian Shi, Li Zhang, Wei Zhen, Wenying Chen, Yonglian Zhang

published 31 Dec 2008

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