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Small interfering RNA

ZNF93 Increases Resistance to ET-743 (Trabectedin; Yondelis®) and PM00104 (Zalypsis®) in Human Cancer Cell Lines

Zhenfeng Duan, Edwin Choy, David Harmon, Cao Yang, Keinosuke Ryu, Joseph Schwab, Henry Mankin, Francis J. Hornicek

published 09 Sep 2009

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Negative Regulators of Insulin Signaling Revealed in a Genome-Wide Functional Screen

Shih-Min A. Huang, Michael K. Hancock, Jeffrey L. Pitman, Anthony P. Orth, Nicholas Gekakis

published 03 Sep 2009

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Regulation of PERK Signaling and Leukemic Cell Survival by a Novel Cytosolic Isoform of the UPR Regulator GRP78/BiP

Min Ni, Hui Zhou, Shiuan Wey, Peter Baumeister, Amy S. Lee

published 31 Aug 2009

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Human Condensin Function Is Essential for Centromeric Chromatin Assembly and Proper Sister Kinetochore Orientation

Alexander Samoshkin, Alexei Arnaoutov, Lars E. T. Jansen, Ilia Ouspenski, Louis Dye, Tatiana Karpova, James McNally, Mary Dasso, Don W. Cleveland, Alexander Strunnikov

published 28 Aug 2009

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microRNA-Mediated Messenger RNA Deadenylation Contributes to Translational Repression in Mammalian Cells

Traude H. Beilharz, David T. Humphreys, Jennifer L. Clancy, Rolf Thermann, David I. K. Martin, Matthias W. Hentze, Thomas Preiss

published 27 Aug 2009

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A Novel Role for IκBζ in the Regulation of IFNγ Production

Raquel M. Raices, Yashaswini Kannan, Vedavathi Bellamkonda-Athmaram, Sudarshan Seshadri, Huating Wang, Denis C. Guttridge, Mark D. Wewers

published 26 Aug 2009

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Expression and Functional Studies of Ubiquitin C-Terminal Hydrolase L1 Regulated Genes

Anjali Bheda, Julia Shackelford, Joseph S. Pagano

published 26 Aug 2009

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Knocking-Down Cyclin A₂ by siRNA Suppresses Apoptosis and Switches Differentiation Pathways in K562 Cells upon Administration with Doxorubicin

Xiaohui Wang, Yujun Song, Jinsong Ren, Xiaogang Qu

published 17 Aug 2009

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RNA Silencing of Mcl-1 Enhances ABT-737-Mediated Apoptosis in Melanoma: Role for a Caspase-8-Dependent Pathway

Angela M. Keuling, Kathleen E. A. Felton, Arabesque A. M. Parker, Majid Akbari, Susan E. Andrew, Victor A. Tron

published 17 Aug 2009

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CK2 Is the Regulator of SIRT1 Substrate-Binding Affinity, Deacetylase Activity and Cellular Response to DNA-Damage

Hyeog Kang, Jae-Won Jung, Myung K. Kim, Jay H. Chung

published 14 Aug 2009

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ER Stress-Inducible Factor CHOP Affects the Expression of Hepcidin by Modulating C/EBPalpha Activity

Susana J. Oliveira, Jorge P. Pinto, Gonçalo Picarote, Vera M. Costa, Félix Carvalho, Maria Rangel, Maria de Sousa, Sérgio F. de Almeida

published 12 Aug 2009

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APOBEC3G-Depleted Resting CD4⁺ T Cells Remain Refractory to HIV1 Infection

Francesca R. Santoni de Sio, Didier Trono

published 10 Aug 2009

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Protein Kinase Cδ Stimulates Proteasome-Dependent Degradation of C/EBPα during Apoptosis Induction of Leukemic Cells

Meng Zhao, Xu-Fang Duan, Xu-Yun Zhao, Bo Zhang, Ying Lu, Wei Liu, Jin-Ke Cheng, Guo-Qiang Chen

published 07 Aug 2009

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