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Small interfering RNA

Cholinergic Receptor Nicotinic Alpha 5 (CHRNA5) RNAi is associated with cell cycle inhibition, apoptosis, DNA damage response and drug sensitivity in breast cancer

Sahika Cingir Koker, Ermira Jahja, Huma Shehwana, Ayse Gokce Keskus, Ozlen Konu

published 13 Dec 2018

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Transcriptional profiling identifies novel regulators of macrophage polarization

Kimberline Y. Gerrick, Elias R. Gerrick, Anuj Gupta, Sarah J. Wheelan, Srinivasan Yegnasubramanian, Elizabeth M. Jaffee

published 07 Dec 2018

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Effects of acute hypoxia exposure with different durations on activation of Nrf2-ARE pathway in mouse skeletal muscle

Weixiu Ji, Linjia Wang, Shiyi He, Lu Yan, Tieying Li, Jianxiong Wang, Ah-Ng Tony Kong, Siwang Yu, Ying Zhang

published 04 Dec 2018

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NRF2-regulated cell cycle arrest at early stage of oxidative stress response mechanism

Margita Márton, Nikolett Tihanyi, Pál Gyulavári, Gábor Bánhegyi, Orsolya Kapuy

published 28 Nov 2018

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Differential roles of gangliosides in malignant properties of melanomas

Yuhsuke Ohmi, Mariko Kambe, Yuki Ohkawa, Kazunori Hamamura, Orie Tajima, Rika Takeuchi, Koichi Furukawa, Keiko Furukawa

published 21 Nov 2018

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Akt2 causes TGFβ-induced deptor downregulation facilitating mTOR to drive podocyte hypertrophy and matrix protein expression

Falguni Das, Nandini Ghosh-Choudhury, Doug Yoon Lee, Yves Gorin, Balakuntalam S. Kasinath, Goutam Ghosh Choudhury

published 16 Nov 2018

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Clathrin adaptor GGA1 modulates myogenesis of C2C12 myoblasts

Mari Isobe, Sachiko Lee, Satoshi Waguri, Satoshi Kametaka

published 15 Nov 2018

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CRB3 and the FERM protein EPB41L4B regulate proliferation of mammary epithelial cells through the release of amphiregulin

Stephanie J. Walker, Laura M. Selfors, Ben L. Margolis, Joan S. Brugge

published 15 Nov 2018

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Cytokine-induced cysteine- serine-rich nuclear protein-1 (CSRNP1) selectively contributes to MMP1 expression in human chondrocytes

Christopher D. Macdonald, Adrian M. D. Falconer, Chun Ming Chan, David J. Wilkinson, Andrew Skelton, Louise Reynard, Gary J. Litherland, G. Nicholas Europe-Finner, Andrew D. Rowan

published 15 Nov 2018

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The phosphorylation of sorting nexin 5 at serine 226 regulates retrograde transport and macropinocytosis

Nao Itai, Tsukasa Shimazu, Takayuki Kimura, Issei Ibe, Ryo Yamashita, Yasushi Kaburagi, Taeko Dohi, Takashi Tonozuka, Toshifumi Takao, Atsushi Nishikawa

published 12 Nov 2018

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DNMTs and SETDB1 function as co-repressors in MAX-mediated repression of germ cell–related genes in mouse embryonic stem cells

Daiki Tatsumi, Yohei Hayashi, Mai Endo, Hisato Kobayashi, Takumi Yoshioka, Kohei Kiso, Shinichiro Kanno, Yuji Nakai, Ikuma Maeda, Kentaro Mochizuki, Makoto Tachibana, Haruhiko Koseki, Akihiko Okuda, Akira Yasui, Tomohiro Kono, Yasuhisa Matsui

published 07 Nov 2018

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Loss of BAP1 expression is associated with genetic mutation and can predict outcomes in gallbladder cancer

Takashi Hirosawa, Masaharu Ishida, Kentaro Ishii, Keigo Kanehara, Katsuyoshi Kudo, Shinobu Ohnuma, Takashi Kamei, Fuyuhiko Motoi, Takeshi Naitoh, Florin M. Selaru, Michiaki Unno

published 05 Nov 2018

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Methylation dependent down-regulation of G0S2 leads to suppression of invasion and improved prognosis of IDH1-mutant glioma

Takanori Fukunaga, Yuki Fujita, Haruhiko Kishima, Toshihide Yamashita

published 02 Nov 2018

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