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Small interfering RNA

Enarodustat suppresses thymic stromal lymphopoietin expression via hypoxia-inducible factor-mediated c-Jun N-terminal kinases dephosphorylation

Ryosuke Segawa, Makiko Yagisawa, Chihiro Miyata, Noriyasu Hirasawa

published 23 Jan 2026

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Evaluation of rat pancreatic islets damage after siRNA microporation

Veronika Tomsovska, Ivan Leontovyc, Klara Zacharovova, Eva Fabryova, Tomas Koblas, Zuzana Berkova, Jan Kriz

published 23 Jan 2026

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RIPK2 induces docetaxel resistance in prostate cancer through the NF-κB/P-gp signaling pathway

Shaoqiang Xing, Zhaoliang Xu, Sheng Zeng, Minghao Yue, Wenzhou Xing, Qian Liu

published 21 Jan 2026

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Multi-omics analysis and functional validation of CHEK1 as an independent prognostic biomarker in Pancreatic cancer

Xiaonan Wei, Ruirong Yan, Shanshan Wang, Yaru Jiang, Haibin Li, Yanping Li

published 21 Jan 2026

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DC-STAMP activates the PI3K/AKT/mTOR signaling pathway to regulate PANoptosis in acute myeloid leukemia

Qian Liang, Biao Li, Yue Li, Longhui Ma, Li Dong, Ning Ding, Wei Zhang, Haoran Wang, Junying Liu

published 16 Jan 2026

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Far-infrared irradiation attenuates vessel contraction by activating SERCA2 through disruption of SERCA2 and PLN interaction

Yun-Jin Hwang, So-Young Park, Jung-Hyun Park, Du-Hyong Cho

published 17 Dec 2025

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UTX/Top2β axis mediated spinal cord microvascular endothelial cells senescence exacerbates spinal cord injury

Dongliang Liu, Yudong Liu, Tianding Wu, Jianzhong Hu

published 12 Dec 2025

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Inflammatory cytokines promote interferon regulatory factor (IRF) transcriptional activity in human pulmonary epithelial cells through the induction of IRF1 by nuclear factor-κB

Amandah Necker-Brown, Mahmoud M. Mostafa, Andrei Georgescu, Andrew J. Thorne, Priyanka Chandramohan, Cora Kooi, Keerthana Kalyanaraman, Alex Gao, Akanksha Bansal, Sarah K. Sasse, Anthony N. Gerber, Richard Leigh, Robert Newton

published 08 Dec 2025

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Exosomes from bone marrow mesenchymal stem cells protect melanocytes under vitiligo-related conditions through induction of NRF2/HO1 expression

Xuecheng Sun, Bo Huang, Gaobo Ruan, Aie Xu

published 04 Dec 2025

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Autophagy regulates MK-2206-induced LDL receptor expression and cholesterol efflux pathways

Hilde Sundvold, Thea Bismo Strøm

published 04 Dec 2025

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Nucleic acid-induced chemokine expression in keratinocytes: Implications for skin inflammation

Judit Danis, Evelyn Kelemen, Fanni Balogh, Kornélia Szabó, Gergely H. Fodor, Éva Ádám, Márta Széll

published 20 Nov 2025

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Identification and validation of the important role of tryptophan-related gene CYP1B1 in the development and progression of sepsis

Li-Hong Chen, Wei-Ru Lin, Hui-Rong Hu, Zhi-Yuan Chen, Yan-Hui Wang

published 10 Nov 2025

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Ionizing radiation leads to exosome secretion in macrophages through MYC-mediated pathways

Hanui Lee, Gyeong Han Jeong, Geun-Joong Kim, Seung Sik Lee, Byung Yeoup Chung, Hyoung-Woo Bai

published 05 Nov 2025

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