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Small interfering RNA

Cleavage of MALAT1 RNA by 14-nt sgRNA-guided tRNase Z^L

Masayuki Takahashi, Masayuki Nashimoto

C3AR1 may aggravate diabetic nephropathy by mediating oxidative stress via ITGB2 regulation in renal tubular epithelial cells

Alex Abura, Shan Gao

TGFBR1 gene silencing attenuates cardiomyopathy in the HFpEF mouse model

Xuanyang Shen, Weidong Li, [ ... ], Guoping Kang

Piezo1 regulates autophagy in HT22 hippocampal neurons through the Ca²⁺/Calpain and Calcineurin/TFEB signaling pathways

Yatong Wu, Yan Lu, [ ... ], Shimin Yin

Downregulation of NCOA4 expression indicates poor prognosis and promotes the progression of cholangiocarcinoma

Wenlong Shen, Yi Liu, [ ... ], Chi Liu

The FGFR inhibitor pemigatinib overcomes cancer drug resistance to KRAS G12C inhibitors in mesenchymal lung cancer

Angela Abdollahi, Margaret Favata, [ ... ], Alejandro Amador-Arjona

Daraxonrasib, a pan-RAS inhibitor, selectively inhibits osteosarcomas with activated KRAS by halting AKT signaling and matrix metalloprotease activity

Okkeun Jung, Angelene Soto, Andrew L. Wolfe, Shahana S. Mahajan

Role of G-protein-coupled receptor kinase 4 on the dysfunction of renal Mas receptor in hypertension

Lin Chen, Jiayao Chen, [ ... ], Jian Yang

Cellular repressor of E1A-stimulated genes 1 enhances skeletal muscle performance through the stimulation of muscle differentiation and Akt-mTOR signaling pathway activation

Ayumi Goto, Michihiro Hashimoto, [ ... ], Hitoshi Yamashita

IQGAP1 participates in endothelial cell apoptosis and regulates atherosclerosis by targeting YAP

Shaojun Huang, Yao Cheng, Chengxin Zhang

MTMR7 regulates human spermatogonial stem cells proliferation and migration via targeting FLNB

Nianchao Zhou, Tiantian Wu, [ ... ], Tingting Gao

Reciprocal effects of conditioned medium on gene and protein expression of limbal epithelial cells and limbal fibroblasts in congenital aniridia

Maximilian Berger, Nóra Szentmáry, [ ... ], Tanja Stachon

Galectin-3 inhibition ameliorates hepatic steatosis in a multilineage 3D spheroid model

Francesca Sedda, Andrea Caddeo, [ ... ], Andrea Perra

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