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Small interfering RNA

Linker region is required for efficient nuclear localization of polynucleotide kinase phosphatase

Kaima Tsukada, Yoshihisa Matsumoto, Mikio Shimada

published 24 Sep 2020

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Flavopiridol causes cell cycle inhibition and demonstrates anti-cancer activity in anaplastic thyroid cancer models

Nicole Pinto, Stephenie D. Prokopec, Farhad Ghasemi, Jalna Meens, Kara M. Ruicci, Imran M. Khan, Neil Mundi, Krupal Patel, Myung W. Han, John Yoo, Kevin Fung, Danielle MacNeil, Joe S. Mymryk, Alessandro Datti, John W. Barrett, Paul C. Boutros, Laurie Ailles, Anthony C. Nichols

published 24 Sep 2020

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Eps15 Homology Domain Protein 4 (EHD4) is required for Eps15 Homology Domain Protein 1 (EHD1)-mediated endosomal recruitment and fission

Tyler Jones, Naava Naslavsky, Steve Caplan

published 23 Sep 2020

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Detection of acute toxicity of aflatoxin B1 to human hepatocytes in vitro and in vivo using chimeric mice with humanized livers

Yuji Ishida, Chihiro Yamasaki, Hiroko Iwanari, Hisahiko Yamashita, Yuko Ogawa, Ami Yanagi, Suzue Furukawa, Yuha Kojima, Kazuaki Chayama, Junichi Kamiie, Chise Tateno

published 23 Sep 2020

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Reticulon-3 modulates the incorporation of replication competent hepatitis C virus molecules for release inside infectious exosomes

Jingjing Li, Ebtisam Abosmaha, Carla S. Coffin, Patrick Labonté, Terence Ndonyi Bukong

published 17 Sep 2020

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Melasolv induces melanosome autophagy to inhibit pigmentation in B16F1 cells

Hyun Jun Park, Doo Sin Jo, Hyunjung Choi, Ji-Eun Bae, Na Yeon Park, Joon Bum Kim, Ji Yeon Choi, Yong Hwan Kim, Gyeong Seok Oh, Jeong Ho Chang, Hyoung-June Kim, Dong-Hyung Cho

published 17 Sep 2020

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The metronomic combination of paclitaxel with cholinergic agonists inhibits triple negative breast tumor progression. Participation of M₂ receptor subtype

Alejandro J. Español, Agustina Salem, María Di Bari, Ilaria Cristofaro, Yamila Sanchez, Ada M. Tata, María E. Sales

published 10 Sep 2020

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MITF and TFEB cross-regulation in melanoma cells

Josué Ballesteros-Álvarez, Ramile Dilshat, Valerie Fock, Katrín Möller, Ludwig Karl, Lionel Larue, Margrét Helga Ögmundsdóttir, Eiríkur Steingrímsson

published 03 Sep 2020

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Activation of GPR56, a novel adhesion GPCR, is necessary for nuclear androgen receptor signaling in prostate cells

Julie Pratibha Singh, Manisha Dagar, Gunjan Dagar, Sudhir Kumar, Sudhir Rawal, Ravi Datta Sharma, Rakesh Kumar Tyagi, Gargi Bagchi

published 03 Sep 2020

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ATM and P53 differentially regulate pancreatic beta cell survival in Ins1E cells

Celina Uhlemeyer, Nadine Müller, Kerstin Grieß, Corinna Wessel, Caroline Schlegel, Jennifer Kuboth, Bengt-Frederik Belgardt

published 18 Aug 2020

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Lactic acid bacterium, Lactobacillus paracasei KW3110, suppresses inflammatory stress-induced caspase-1 activation by promoting interleukin-10 production in mouse and human immune cells

Takahiro Yamazaki, Konomi Ohshio, Miho Sugamata, Yuji Morita

published 17 Aug 2020

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Assessment of STAT5 as a potential therapy target in enzalutamide-resistant prostate cancer

Holger H. H. Erb, Julia Bodenbender, Florian Handle, Tamara Diehl, Lukas Donix, Igor Tsaur, Martin Gleave, Axel Haferkamp, Johannes Huber, Susanne Fuessel, Eva Juengel, Zoran Culig, Christian Thomas

published 13 Aug 2020

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Secretome analysis reveals upregulated granzyme B in human androgen-repressed prostate cancer cells with mesenchymal and invasive phenotype

Mayassa J. Bou-Dargham, Qing-Xiang Amy Sang

published 07 Aug 2020

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