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Scrapie

Proliferative arrest induces neuronal differentiation and innate immune responses in normal and Creutzfeldt-Jakob Disease agent (CJ) infected rat septal neurons

Nathan Pagano, Gerard Aguilar Perez, Rolando Garcia-Milian, Laura Manuelidis

published 28 May 2025

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Temporal serum neurofilament light chain concentrations in sheep inoculated with the agent of classical scrapie

Quazetta Brown, Eric Nicholson, Chong Wang, Justin Greenlee, Hannah Seger, Susan Veneziano, Eric Cassmann

published 23 Feb 2024

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Efficacy of Wex-cide 128 disinfectant against multiple prion strains

Chase Baune, Bradley R. Groveman, Andrew G. Hughson, Tina Thomas, Barry Twardoski, Suzette Priola, Bruce Chesebro, Brent Race

published 24 Aug 2023

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Field demonstration analyzing the implementation of individual animal electronic identification and genetic testing in western range sheep flocks

Julie A. Finzel, Austin R. Brown, Roselle C. Busch, Morgan P. Doran, John M. Harper, Daniel K. Macon, Rebecca K. Ozeran, Morgan R. Stegemiller, Karissa Isaacs, Alison Van Eenennaam

published 23 Aug 2023

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PrP^res in placental tissue following experimental transmission of atypical scrapie in ARR/ARR sheep is not infectious by Tg338 mouse bioassay

Robert B. Piel III, Valerie R. McElliott, James B. Stanton, Dongyue Zhuang, Sally A. Madsen-Bouterse, Linda K. Hamburg, Robert D. Harrington, David A. Schneider

published 21 Jan 2022

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Large-scale survey of prion protein genetic variability in scrapie disease-free goats from the United States

Mohamed Zeineldin, Kimberly Lehman, Natalie Urie, Matthew Branan, Alyson Wiedenheft, Katherine Marshall, Suelee Robbe-Austerman, Tyler Thacker

published 19 Jul 2021

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Transmission of the atypical/Nor98 scrapie agent to Suffolk sheep with VRQ/ARQ, ARQ/ARQ, and ARQ/ARR genotypes

Eric D. Cassmann, Najiba Mammadova, S. Jo Moore, Sylvie Benestad, Justin J. Greenlee

published 11 Feb 2021

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Autoclave treatment of the classical scrapie agent US No. 13-7 and experimental inoculation to susceptible VRQ/ARQ sheep via the oral route results in decreased transmission efficiency

Eric D. Cassmann, Najiba Mammadova, Justin J. Greenlee

published 03 Dec 2020

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Neurofilaments in blood is a new promising preclinical biomarker for the screening of natural scrapie in sheep

Henrik Zetterberg, Elena Bozzetta, Alessandra Favole, Cristiano Corona, Maria Concetta Cavarretta, Francesco Ingravalle, Kaj Blennow, Maurizio Pocchiari, Daniela Meloni

published 19 Dec 2019

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Quaking-induced conversion of prion protein on a thermal mixer accelerates detection in brains infected with transmissible spongiform encephalopathy agents

Nadine Kaelber, Cyrus Bett, David M. Asher, Luisa Gregori

published 12 Dec 2019

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Toll-like receptor 2 confers partial neuroprotection during prion disease

James A. Carroll, Brent Race, Katie Williams, Bruce Chesebro

published 31 Dec 2018

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Source genotype influence on cross species transmission of transmissible spongiform encephalopathies evaluated by RT-QuIC

Soyoun Hwang, Justin J. Greenlee, Natalie M. Vance, Eric M. Nicholson

published 20 Dec 2018

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Prion-like protein gene (PRND) polymorphisms associated with scrapie susceptibility in Korean native black goats

Min-Ju Jeong, Yong-Chan Kim, Byung-Hoon Jeong

published 25 Oct 2018

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