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Sarcoma cells

Fluorescence-guided assessment of bone and soft-tissue sarcomas for predicting the efficacy of telomerase-specific oncolytic adenovirus

Koji Uotani, Hiroshi Tazawa, Joe Hasei, Tomohiro Fujiwara, Aki Yoshida, Yasuaki Yamakawa, Toshinori Omori, Kazuhisa Sugiu, Tadashi Komatsubara, Hiroya Kondo, Takuya Morita, Masahiro Kiyono, Suguru Yokoo, Toshiaki Hata, Toshiyuki Kunisada, Ken Takeda, Yasuo Urata, Toshiyoshi Fujiwara, Toshifumi Ozaki

published 20 Feb 2024

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AT-hook DNA-binding motif-containing protein one knockdown downregulates EWS-FLI1 transcriptional activity in Ewing’s sarcoma cells

Takao Kitagawa, Daiki Kobayashi, Byron Baron, Hajime Okita, Tatsuo Miyamoto, Rie Takai, Durga Paudel, Tohru Ohta, Yoichi Asaoka, Masayuki Tokunaga, Koji Nakagawa, Makoto Furutani-Seiki, Norie Araki, Yasuhiro Kuramitsu, Masanobu Kobayashi

published 04 Oct 2022

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Growth inhibition associated with disruption of the actin cytoskeleton by Latrunculin A in rhabdomyosarcoma cells

Julia Würtemberger, Daria Tchessalova, Carla Regina, Christoph Bauer, Michaela Schneider, Amy J. Wagers, Simone Hettmer

published 08 Sep 2020

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Radiation synergizes with antitumor activity of CD13-targeted tissue factor in a HT1080 xenograft model of human soft tissue sarcoma

Caroline Brand, Burkhard Greve, Tobias Bölling, Hans T. Eich, Normann Willich, Saliha Harrach, Heike Hintelmann, Georg Lenz, Rolf M. Mesters, Torsten Kessler, Christoph Schliemann, Wolfgang E. Berdel, Christian Schwöppe

published 21 Feb 2020

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Target specificity, in vivo pharmacokinetics, and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma

Peter Y. Yu, Heather L. Gardner, Ryan Roberts, Hakan Cam, Seethalakshmi Hariharan, Ling Ren, Amy K. LeBlanc, Hui Xiao, Jiayuh Lin, Denis C. Guttridge, Xiaokui Mo, Chad E. Bennett, Christopher C. Coss, Yonghua Ling, Mitch A. Phelps, Peter Houghton, Cheryl A. London

published 27 Jul 2017

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HDAC and Proteasome Inhibitors Synergize to Activate Pro-Apoptotic Factors in Synovial Sarcoma

Aimée N. Laporte, Jared J. Barrott, Ren Jie Yao, Neal M. Poulin, Bertha A. Brodin, Kevin B. Jones, T. Michael Underhill, Torsten O. Nielsen

published 05 Jan 2017

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Persistent Morbillivirus Infection Leads to Altered Cortactin Distribution in Histiocytic Sarcoma Cells with Decreased Cellular Migration Capacity

Vanessa Maria Pfankuche, Mohamed Sayed-Ahmed, Vanessa Bono Contioso, Ingo Spitzbarth, Karl Rohn, Reiner Ulrich, Ulrich Deschl, Arno Kalkuhl, Wolfgang Baumgärtner, Christina Puff

published 02 Dec 2016

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Preclinical Evidence of Anti-Tumor Activity Induced by EZH2 Inhibition in Human Models of Synovial Sarcoma

Satoshi Kawano, Alexandra R. Grassian, Masumi Tsuda, Sarah K. Knutson, Natalie M. Warholic, Galina Kuznetsov, Shanqin Xu, Yonghong Xiao, Roy M. Pollock, Jesse S. Smith, Kevin K. Kuntz, Scott Ribich, Yukinori Minoshima, Junji Matsui, Robert A. Copeland, Shinya Tanaka, Heike Keilhack

published 08 Jul 2016

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Down-Regulation of AKT Signalling by Ursolic Acid Induces Intrinsic Apoptosis and Sensitization to Doxorubicin in Soft Tissue Sarcoma

Victor Hugo Villar, Oliver Vögler, Francisca Barceló, Javier Martín-Broto, Jordi Martínez-Serra, Valentina Ruiz-Gutiérrez, Regina Alemany

published 24 May 2016

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Impact of Mistletoe Triterpene Acids on the Uptake of Mistletoe Lectin by Cultured Tumor Cells

Katharina Mulsow, Thomas Enzlein, Catharina Delebinski, Sebastian Jaeger, Georg Seifert, Matthias F. Melzig

published 18 Apr 2016

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Evaluation of In Vitro Activity of the Class I PI3K Inhibitor Buparlisib (BKM120) in Pediatric Bone and Soft Tissue Sarcomas

Jennifer L. Anderson, Ann Park, Ryan Akiyama, William D. Tap, Christopher T. Denny, Noah Federman

published 24 Sep 2015

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IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas

Xin Huang, Haein Park, Joseph Greene, James Pao, Erin Mulvey, Sophia X. Zhou, Catherine M. Albert, Fred Moy, Deepali Sachdev, Douglas Yee, Christoph Rader, Carl V. Hamby, David M. Loeb, Mitchell S. Cairo, Xianzheng Zhou

published 14 Jul 2015

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Human Sarcoma Growth Is Sensitive to Small-Molecule Mediated AXIN Stabilization

Alessandra De Robertis, Federica Mennillo, Marco Rossi, Silvia Valensin, Patrizia Tunici, Elisa Mori, Nicola Caradonna, Maurizio Varrone, Massimiliano Salerno

published 19 May 2014

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