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Routes of administration

Development of a protocol for intravenous infusion management in patients with aggressive behavior due to mental disorders: A Donabedian framework approach

Liying Liu, Yaling Sun, Yujie Hao, Wanyu Zhang, Yan Gao, Yulian Wei, Lina Wang, Honghui Wang

published 21 May 2026

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A novel application tunnel in combination with medical training reduces stress induced by frequent intraperitoneal injections and blood draws in mice

Anne Schlutt, Katarina Riesner, Merle Kochan, Ann-Kathrin Meß, Denise Jahn, Isabella Lurje, Wiebke Werner, Felix Heymann, Olivia Kershaw, Frank Tacke, Bernhard Hiebl, Linda Hammerich

published 07 May 2026

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Machine learning-based unified models for predicting drug clearance from pharmacokinetic animal and study design variables

Remya Ampadi Ramachandran, Lisa A. Tell, Melissa A. Mercer, Xuan Xu, Nuwan Indika Millagaha Gedara, Maaike Ottoline Clapham, Zhoumeng Lin, Jim E. Riviere, Majid Jaberi-Douraki

published 06 May 2026

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Oral step-down vs full-course intravenous antibiotic therapy for infective endocarditis: Protocol for a systematic review and meta-analysis

Jose D. Cruz-Cuevas, Julián Andrés Amador Bedoya, María Paula Méndez Gaitán, María Camila Ramírez, Javier González Quiroga, Adelaida Rodríguez Villegas, Antonia Sanín Reyes

published 29 Apr 2026

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A single dose of purified human antibody from transchromosomic bovines mitigates aerosolized Venezuelan equine encephalitis virus disease in cynomolgus macaques

Chengqun Sun, Christina Gardner, Long Kwan Metthew Lam, Jeneveve Lundy, Katherine O’Malley, Thomas Luke, Kanakatte Raviprakash, Amy L. Hartman, Nicholas A. Crossland, Hua Wu, Jin-an Jiao, Christoph Bausch, Eddie Sullivan, Douglas S. Reed, William B. Klimstra

published 27 Apr 2026

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Intraperitoneal administration of NK-92 improves survival in xenografts of early and established ovarian cancer models

Paula Marcus, Jenny Warrington, Michael Zhang, Manjunatha Ankathatti-Munegowda, Xing-Hua Wang, Iran Rashedi, Armand Keating

published 20 Apr 2026

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Exploring scalable assessment methods for terminated trials in ClinicalTrials.gov: A cohort analysis of German and Californian trials

Samruddhi Suresh Yerunkar, Benjamin Gregory Carlisle, Delwen L. Franzen, Maia Salholz-Hillel, Daniel Strech, Susanne Gabriele Schorr

published 15 Apr 2026

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Adverse events in different administration routes of Edaravone: A pharmacovigilance study based on the FDA adverse event reporting system

Deye Ge, Liyan Wu, Jingrong Yang, Jingxian Sun, Jinying Wang, Jingxin Wang, Huihui Song, Ran Wei, Zecheng Xu, Binbin Zhao, Rongfei Sun, Yifei Wang

published 13 Apr 2026

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Clinical impact of broad- versus narrow-spectrum empiric therapy in acute cholangitis: A Japanese claims database study

Kazuhiro Aoto, Ryo Inose, Yuichi Muraki

published 02 Apr 2026

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Inhibition of transient receptor potential vanilloid 1 (TRPV1) by a novel selective antagonist for anti-nociceptive effect on inflammatory pain without hyperthermia

Jialiang Guan, Chenru Zhao, Qiqi Zhou, Chao Zhu

published 25 Mar 2026

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Assessment of a baloxavir marboxil treatment protocol for high pathogenicity avian influenza in Okinawa Rails, an endangered species endemic to Japan

Mariko Miki, Yo Shimazu, Ryo Daniel Obara, Takashi Nagamine, Yumiko Nakaya, Yoshinori Ikenaka, Hiromi Osaki, Takashi Kimura, Takahiro Hiono, Norikazu Isoda, Takao Shishido, Yoshihiro Sakoda

published 23 Mar 2026

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Intravenous thrombolysis for acute central retinal artery occlusion: Protocol for a systematic review and individual participant data meta-analysis of randomized controlled trials

Brian Mac Grory, Cécile Preterre, Pierre Lebranchu, Stephen James Ryan, Øystein Kalsnes Jørstad, Morten Carstens Moe, Johannes Tünnerhoff, Martin S. Spitzer, Carsten Grohmann, Oana M. Dumitrascu, Valérie Biousse, Benoit Guillon, Anne Hege Aamodt, Sven Poli, Matthew Schrag, The Central Retinal ArterY OcclusioN (CRAYON) Collaborators

published 10 Mar 2026

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Therapeutic effect and mechanism of different doses of aspirin on preterm delivery in pregnant mice

Xinlan Qu, Xuechun Wu, Xiaomeng Pang, Yuan Fang

published 05 Mar 2026

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