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Regulatory proteins

System biology and network-based approach to identify the therapeutic signatures and potential inhibitors against polycystic lipomembranous osteodysplasia with Sclerosing Leukoencephalopathy

Bayan T. Bokhari, Alaa M. Saleh, Hashim M. Aljohani, Wejdan Hussain Owaydhah, Mohammad Ahmad Alobaidy, Naief Dahran, Hind M. Naffadi, Alaa Abdulaziz Eisa

published 20 Feb 2026

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Molecular interplay of ASNS and the PI3K-AKT-mTOR pathway in CMV and HIV co-infections: Therapeutic implications

Hao Zhang, ShuYou Yuan, ShaoXiang Ding, HongXia Bao, WenJun Chen, Bo Cai, JunKai Sun, HaoGang Zhu, Wei Lu, Ye Fang

published 20 Feb 2026

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Rosuvastatin protects against oxLDL-induced endothelial cell oxidative stress and attenuates atherosclerotic plaque formation in ApoE^-/- mice through the NF-κB pathway

Yichen Wu, Jiaqi Ke, Jiaxin Lv, Chaowei Cao, Chunxian Zhou, Lili Wu, Qiyang Zhou

published 20 Feb 2026

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Serum Amyloid A (SAA) induces transcription affecting inflammation

George H. Sack Jr., Joseph Yun, C. Conover Talbot Jr., Jasmeet Sethi

published 19 Feb 2026

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Remdesivir may exacerbate ischemic acute kidney injury through molecular alterations in PGC-1α and apoptosis pathways: An in vivo study

Yasin Bagheri, Zahra Malekinejad, Seyyedeh Mina Hejazian, Abdollah Abdollahpour, Fatemeh Khajepour, Mohaddeseh Farahbod, Sama Ahmadi, Samira Matin, Sepideh Zununi Vahed

published 12 Feb 2026

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GATA4-targeted compounds induce apoptosis and diminish viability of hepatoblastoma cells

Sini M. Kinnunen, Katja Eloranta, Marjut Pihlajoki, Mika J. Välimäki, Saana Pohjavaara, Emilie Indersie, Stefano Cairo, Aarni Kuusinen, Heikki Ruskoaho, Markku Heikinheimo

published 11 Feb 2026

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Proteomic profiling of a Sporobolomyces yeast reveals global responses to UV-B–induced oxidative stress

Ranko Gacesa, Raymond Chung, Suikinai Nobre Santos, Gabriel Padilla, Itamar Soares Melo, Paul F. Long

published 11 Feb 2026

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Computational elucidation of stomidazolone mediated inhibition of stomatal differentiation and its implication in plant developmental regulation

Syeda Sumayya Tariq, Urooj Qureshi, Mamona Mushtaq, Maria Nasim, Mohammad Nur-e-Alam, Tawfeq A. AlHowiriny, Yan Wang, Zaheer Ul-Haq

published 10 Feb 2026

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A multifaceted analysis of OTUD5 integrated MAVS in innate immunity of Primary Biliary Cholangitis

Ran Chen, Yan Sun, Wenlin Tai

published 06 Feb 2026

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Antiviral and anti-inflammatory evaluation of herbal extracts: Implications for the management of calf diarrheal diseases

Xi-Rui Xiang, Eun-Seo Lee, Junho Lee, Su Min Kyung, Han Sang Yoo

published 06 Feb 2026

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Salt loading as a promising approach to study the dopaminergic phenotype of neurons of the supraoptic nucleus in mice

Alyona E. Bannikova, Tatiana S. Pronina, Dmitry V. Troshev, Vsevolod V. Bogdanov, Anna A. Kolacheva, Ekaterina N. Pavlova, Victor E. Blokhin, Varvara I. Kalashnikova, Michael V. Ugrumov

published 06 Feb 2026

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Taurocholic acid induces intrahepatic cholangiocyte cell proliferation via activating NRAS and YAP1

Lum Fube, Arul Thason, Elizabeth Taliaferro, Carol Heckman, Surya Amarachintha

published 04 Feb 2026

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Large-scale multi-omic biosequence transformers for modeling protein–nucleic acid interactions

Sully F. Chen, Robert J. Steele, Glen M. Hocky, Beakal Lemeneh, Shivanand P. Lad, Eric K. Oermann

published 02 Feb 2026

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