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Receptor binding assays

Production of recombinant human G protein-coupled estrogen receptor (GPER) and establishment of a ligand binding assay using graphene quantum dots (GQDs)

Shakhawat Hossain, Md. Forhad Hossain, Md. Sohanur Rahman Sohan, Yuki Omori, Mohammad Tohidul Amin, Toshinobu Tokumoto

published 19 Sep 2025

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Fermented rice germ extract with high concentration of gamma-aminobutyric acid enhances pentobarbital-induced sleep via GABAergic system in rats

Minsook Ye, Woojin Jeong, Hyo Jeong Yu, Kyoung-min Rheu, Bae-jin Lee, Insop Shim

published 12 Aug 2025

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The final walk with preptin

Lucie Mrázková, Marta Lubos, Jan Voldřich, Erika Kužmová, Denisa Zrubecká, Petra Gwozdiaková, Miloš Buděšínský, Seiya Asai, Aleš Marek, Jan Pícha, Michaela Tencerová, Michaela Ferenčáková, Glenda Alquicer Barrera, Jakub Kaminský, Jiří Jiráček, Lenka Žáková

published 12 Sep 2024

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Analytical sameness methodology for the evaluation of structural, physicochemical, and biological characteristics of Armlupeg: A pegfilgrastim biosimilar case study

Arati Deshmukh, Rishank Goyal, Kalyana Sundaram, Kaustubh Dange, Tejshri Lakhote, Sanjay Niranjan, Jennifer Bharucha, Ashok Mishra, Bhavesh Vats, Sanjay Tiwari

published 09 Aug 2023

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Analytical comparability to evaluate impact of manufacturing changes of ARX788, an Anti-HER2 ADC in late-stage clinical development

Wayne Yu, Mysore P. Ramprasad, Manoj Pal, Chris Chen, Shashi Paruchuri, Lillian Skidmore, Nick Knudsen, Molly Allen, Ying Buechler

published 10 Jul 2023

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Tracking the incidence and risk factors for SARS-CoV-2 infection using historical maternal booking serum samples

Edward Mullins, Ruth McCabe, Sheila M. Bird, Paul Randell, Marcus J. Pond, Lesley Regan, Eleanor Parker, Myra McClure, Christl A. Donnelly

published 02 Sep 2022

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Preclinical evaluation of a protracted GLP-1/glucagon receptor co-agonist: Translational difficulties and pitfalls

Lotte Simonsen, Jesper Lau, Thomas Kruse, Tingqing Guo, Jim McGuire, Jacob Fuglsbjerg Jeppesen, Kristoffer Niss, Per Sauerberg, Kirsten Raun, Charlotta Dornonville de la Cour

published 04 Mar 2022

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Fc-engineered antibodies with immune effector functions completely abolished

Ian Wilkinson, Stephen Anderson, Jeremy Fry, Louis Alex Julien, David Neville, Omar Qureshi, Gary Watts, Geoff Hale

published 21 Dec 2021

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Bacillus thuringiensis chimeric proteins Cry1A.2 and Cry1B.2 to control soybean lepidopteran pests: New domain combinations enhance insecticidal spectrum of activity and novel receptor contributions

Danqi Chen, William J. Moar, Agoston Jerga, Anilkumar Gowda, Jason S. Milligan, Eric C. Bretsynder, Timothy J. Rydel, James A. Baum, Altair Semeao, Xiaoran Fu, Victor Guzov, Karen Gabbert, Graham P. Head, Jeffrey A. Haas

published 17 Jun 2021

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A radioligand binding assay for the insulin-like growth factor 2 receptor

Pavlo Potalitsyn, Irena Selicharová, Kryštof Sršeň, Jelena Radosavljević, Aleš Marek, Kateřina Nováková, Jiří Jiráček, Lenka Žáková

published 02 Sep 2020

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Evaluating kratom alkaloids using PHASE

Christopher R. Ellis, Rebecca Racz, Naomi L. Kruhlak, Marlene T. Kim, Alexey V. Zakharov, Noel Southall, Edward G. Hawkins, Keith Burkhart, David G. Strauss, Lidiya Stavitskaya

published 03 Mar 2020

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Analysis of equilibrium binding of an orthosteric tracer and two allosteric modulators

Jan Jakubík, Alena Randáková, Esam E. El-Fakahany, Vladimír Doležal

published 27 Mar 2019

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Critical role of the finger loop in arrestin binding to the receptors

Chen Zheng, Jonas Tholen, Vsevolod V. Gurevich

published 15 Mar 2019

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