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Randomized controlled trials

Physical harms in colorectal cancer screening: An overview of the reporting in systematic reviews and randomised controlled trials

Anne Katrine Lykke Bie, Frederik Handberg Juul Martiny, Christian Patrick Jauernik, Or Joseph Rahbek, Sigrid Brisson Nielsen, Emma Grundtvig Gram, Isabella Kindt, John Brandt Brodersen

published 11 Sep 2025

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Protocol for a core outcome set for pharmacological treatments in hospitalised patients with acute viral respiratory infections (COSAVRI)

Declan Devane, Matthias Briel, Sanjay Bhagani, Nadine Boesten, Stephanie Buchholz, Estefania Callejas De Luca, Jeremie Guedj, Anastasia Koryakina, Kavita Kothari, Karine Lacombe, Patrick W. Mallon, Clément R. Massonnaud, Joanne O’Dwyer, Inge Christoffer Olsen, K. M. Saif-Ur-Rahman, Johannes M. Schwenke, James Thomas, Yazdan Yazdanpanah, Lina Zgaga, Julia Louw

published 09 Sep 2025

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The effect of exogenous melatonin and melatonin receptor agonists on intensive care unit and hospital length of stay: A systematic review and meta-analysis

Art Burgess Kelleher, Mark O’Donovan, Deborah O’Doherty, Ros Lavery, Elaine Lehane, Mohamad M. Saab

published 08 Sep 2025

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The Dino Study: Rationale and protocol for a randomized controlled trial of the Incredible Years Dinosaur Program with daily assessments

Rabia R. Chhangur, Eleonore H.M. Smalle, Gerdien van der Zwaag, Egon Dejonckheere

published 08 Sep 2025

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Consumption of sorghum-based products and their impact on blood glucose and satiety in adult patients: A protocol for systematic review and meta-analysis

Guilherme Augusto Loiola Passos, Érica Aguiar Moraes, Luís Carlos Lopes-Junior

published 04 Sep 2025

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An adaptive simulation intervention decreases emergency physician physiologic stress while caring for patients during COVID-19: A randomized clinical trial

Leigh V. Evans, James W. Bonz, Samuel Buck, Jeffrey N. Gerwin, Shacelles Bonner, Suzette Ikejiani, Tatiana Moylan, Melissa Joseph, Gustavo de Oliveira Almeida, Jessica M. Ray, James D. Dziura, Arjun K. Venkatesh, Ambrose H. Wong

published 03 Sep 2025

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Suicide assessment and feasible evidence-based treatments for adolescents living with HIV in Malawi: Protocol for a pilot randomized controlled trial

Melissa A. Stockton, Katherine Waddell, Steven M. Mphonda, Nivedita L. Bhushan, James January, Charles Masulani, Gregory Brown, Michael M. Udedi, Brian W. Pence, Jonathan Chiwanda, Bradley N. Gaynes, Kazione Kulisewa

published 03 Sep 2025

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Investigating the use of a one-page infographic to improve recruitment and retention to the BASIL+ randomised controlled trial: A Study Within a Trial (SWAT)

Lucy Atha, Eloise Ryde, Lauren Burke, Samantha Brady, Kalpita Baird, Leanne Shearsmith, Charlie Peck, Andrew Henry, Caroline Fairhurst, Han-I Wang, Della Bailey, Rebecca Woodhouse, Dean McMillan, Simon Gilbody, David Ekers, Elizabeth Littlewood

published 03 Sep 2025

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Validity of the German version of the Stay Independent Questionnaire applied by telephone interview: A diagnostic accuracy study

Ulrich Thiem, Ingeborg Schlumbohm, Stefan Golgert, Ulrike Dapp, Saskia Otte

published 03 Sep 2025

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Using protection motivation theory to support patient adherence in healthcare settings: A scoping review

Olivia Hawksworth, Jemima Solt, Dowon Jang, Paul Norman, Daniel Hind, Raveen Jayasuriya

published 02 Sep 2025

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Improving adherence to physical activity in treatment-resistant depression: Protocol for a pilot randomized controlled trial of a remotely delivered program

Vanessa K. Tassone, Danika A. Quesnel, Karisa Parkington, Alice Rueda, Josh Martin, Gyu Hee Lee, Alyssa Teixeira, Melissa L. deJonge, Wendy Lou, David Wiljer, Benoit H. Mulsant, Catherine M. Sabiston, Venkat Bhat

published 02 Sep 2025

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Effect of sensory art therapies on root canal treatment anxiety and high dental anxiety in adults: A systematic review with meta-analysis

Shuhan Guo, Xuexing Luo, Jue Wang, Guanghui Huang

published 02 Sep 2025

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Early multimodal vasopressor strategy in septic shock (TRICYCLE)—Study protocol for a randomized controlled clinical trial

Žiga Kalamar, Mario Gorenjak, Giovanni Landoni, Andrej Markota

published 29 Aug 2025

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