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Randomized controlled trials

Systematic review protocol: The effects of theory-based interventions for self-help practices in the management of mild to moderate depression

Asma’ Khalil, Zahir Izuan Azhar, Norley Shuib, Philip Baker, Xin Wee Chen

published 07 Oct 2025

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The efficacy of DPP IV inhibitors as adjunct therapy for patients with auto-immune Diabetes: A systematic review and meta-analysis

Laurette Nakhoul, Tracy Nakhoul, Maria Abi Azar, Frederic Harb, Nancy Fawzi Nakhoul

published 30 Sep 2025

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Investigating the long-term impact of a programme of mindfulness combined with exercise delivered online (MOVE) on individuals living with chronic pain-an exploratory one-year follow-up of a feasibility randomised control trial

Orla Deegan, Mai Yoshitani, Brona Fullen, Maria Gordon, Orla McDonagh, Orlaith Sheerin, Jane Murphy, Oreluwa Oyebode, Ricardo Segurado, Conor Hearty, Maire Brid Casey, Catherine Doody

published 30 Sep 2025

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Study team perspectives on a multisite randomized clinical trial with underserved rural populations: A mixed methods feasibility analysis

Kristina L. Foster, Sarah Sanders, Christi A. Madden, Lacy Malloch, Amy Swango-Wilson, Barbara Jandasek, Maryam Y. Garza, Jaime Baldner, Erin Dawley, Timothy VanWagoner, Jerome Philip Saul, Ann M. Davis

published 26 Sep 2025

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Artificial intelligence as a predictive tool for mental health status: Insights from a systematic review and meta-analysis

Arsalan Humayun, Ashwini M. Madawana, Akram Hassan, Al Mahmud, Noorshaida Kamaruddin, Syed Husni Noor, Syed Hatim Noor, Mohamad Arif Awang Nawi

published 26 Sep 2025

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Effects of digital health counseling and behavioral interventions on weight management during pregnancy and postpartum: A systematic review and meta-analysis of randomized controlled trials

Sahar Khademioore, Alexandra M. Palumbo, Ahmad Sofi-Mahmudi, Taylor Incze, Kiara Pannozzo, Nicolette Christodoulakis, Rohan D’Souza, Gian Paolo Morgano, Nancy Santesso, Laura N. Anderson

published 25 Sep 2025

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The efficacy and safety of electrical acupoint stimulation (EAS) for knee osteoarthritis (KOA): A GRADE-assessed systematic review, meta-analysis and trial sequential analysis

Guangyi Yang, Rong Zhang, Botan Xu, Yi Yang, Yuxuan Wang, Wenjing Xu, Pengwei Li, Aotian Yu, Simin Ning, Qixuan Fu, Jianfeng Tu

published 25 Sep 2025

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The effect of a six-month programme of intradialytic cycling on survival and hospitalisations in people requiring haemodialysis: 5-year follow-up of the CYCLE-HD randomised controlled trial

Sherna F. Adenwalla, Hannah M. Worboys, Daniel Lawday, Laura J. Gray, Katherine L. Hull, Darren R. Churchward, Patrick J. Highton, Hannah M. L. Young, Matthew P. M. Graham-Brown, James O. Burton, Daniel S. March

published 22 Sep 2025

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Efficacy and neural mechanism of acupuncture for essential hypertension: Study protocol for a randomized clinical trial

Xiao-Ya Wei, Xin-Yuan Jiang, Lu Wang, Chao-Qun Yan, Na-Na Yang, Ze-Yi Wang, Xiao Wang, Hang Zhou, Chih-Kai Lee, Cun-Zhi Liu, Xu Wang, Jian-Feng Tu

published 19 Sep 2025

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Randomized controlled trial on improving pesticide label interpretation among farmers in Akkar Governorate, Lebanon: The impact of a whatsapp-delivered educational video

Nisreen Hassan Akkouch, Jalal Halwani, Issam Shaarani, Fouad Ziadeh

published 18 Sep 2025

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Exercise therapy to improve cervical proprioception in individuals with asymptomatic forward head posture: A systematic review of randomized controlled trials

Ali Asghar Norasteh, Kimia Karimi, Shabnam Faraji, Fereshteh Ejlali, Mohammad Alghosi, Mohammad Alimoradi, Hamed Zarei

published 18 Sep 2025

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Families with neurodevelopmental diagnoses are not ‘Hard to Reach’: Findings from a feasibility trial comparing parenting programmes for parents of children with ADHD

Fiona Sim, Lindsay Dalgarno, Emma McIntosh, Caroline Haig, Patrycja Duklas, Alex McConnachie, Christopher Gillberg, Helen Minnis, Lucy Thompson

published 17 Sep 2025

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Comparison of laparoscopic tubal-preserving surgical management versus methotrexate therapy for tubal pregnancy: A conventional and network meta-analysis

Junwei Liao, Yong Lin, Yan Long

published 12 Sep 2025

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