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Randomized controlled trials

Ketogenic diet therapies for the treatment of drug-resistant epilepsy in children and adults: A systematic review

María Magdalena Vaccarezza, Verónica Laura Sanguine, Giselle Balaciano

published 02 Jul 2026

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Monotherapy or combinations? Intravenous vitamin C in sepsis and septic shock: An umbrella review of 31 systematic reviews

Víctor Juan Vera-Ponce, Jhosmer Ballena-Caicedo, Lupita Ana Maria Valladolid-Sandoval, Fiorella E. Zuzunaga-Montoya, Renzo Acosta-Porzoliz, Oriana Rivera-Lozada, Mario J. Valladares-Garrido

published 01 Jul 2026

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Effects of transcutaneous auricular vagus nerve stimulation combined with repetitive facilitative exercise on lower limb motor function in patients with intracerebral hemorrhage: A pilot randomized controlled trial

Hanji Chen, Hanbo Chen, Chongrui Feng, Jiafa Liu, Xiaoli Li, Gengbiao Zhang, Zhanhao Liu, Mengyun Li

published 30 Jun 2026

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Incidence of depression in patients with psoriasis and psoriatic arthritis treated with biologic therapy: Protocol for a systematic review and meta-analysis

Emily Sirotich, Weston Lowry, Shi-Yi Wang, Madison Jurgens, Jeffrey M. Cohen

published 29 Jun 2026

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Determinants of dropout from lifestyle interventions for overweight polycystic ovary syndrome: An exploratory analysis of randomized controlled trial

Min Xie, Siyu Zhou, Jing Wu, Xiaoyan Luo, Yichuan Guo, Lin Qiao, Jing Zhang

published 26 Jun 2026

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Efficacy of adjunctive antibiotics compared to non-antibiotic therapies following mechanical debridement for peri-implantitis: A systematic review and meta-analysis of randomized controlled trials

Caiyun Liu, Hongtao Wang, Yulan Li, Zhilong Huang, Jian Sun, Han Cai

published 25 Jun 2026

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Inhaled nitric oxide in fibrotic and advanced interstitial lung disease: A systematic review and meta-analysis of randomized controlled trials

Shun Nakahara, Yusuke Hirao, Bradley Fujiuchi, Brent Matsuda

published 22 Jun 2026

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Implementing a patient-oriented pole walking intervention in retirement homes: A non-randomized feasibility trial

Mohsen Keramati, Mahdi Rostami Haji Abadi, Saija Kontulainen

published 17 Jun 2026

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A randomized controlled trial of N-acetylcysteine in the treatment of early-onset preeclampsia: Study Protocol

Kehinde S. Okunade, Adebola A. Adejimi, Muisi A. Adenekan, Iyabo Y. Ademuyiwa, Hameed Adelabu, Fatimah M. Habeebu-Adeyemi, Adaiah P. Soibi-Harry, Ololade Onasanya, Ayomide I. Fayinto, Temitope V. Adekanye, Fatimah Adeboje-Jimoh, Oziegbe Oghide, Nosimot O. Davies, Packson Akhenamen, Festus O. Olowoselu, Babasola O. Okusanya

published 17 Jun 2026

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Understanding participants’ experiences of a behaviour change intervention within cardiac rehabilitation: A nested process evaluation within the STRENGTH randomised controlled trial

Clare T. M. Doherty, Mark A. Tully, Jason J. Wilson, Victoria Irving, Lisa Spratt, Rachel O’Reilly, Kim Kensett, Nicole E. Blackburn

published 16 Jun 2026

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Participatory Rapid Appraisal and Focus Groups to co-design technology-supported integrated care

Bridget O’ Sullivan, Paul Davis, Regina Connolly, Shane O’ Hanlon, Marije Hamaker, Hans Wilders, Cindy Kenis, Una Kearns, Trudy Corrigan, Ciara White, Eleonore Lehn, Marianne Gros, Lucia Ferrara, Vittoria Ardito, Celia Fourrier, Pierre Soubeyron, Siri Rostoft, Vincent Thevenet, Anthony Staines

published 16 Jun 2026

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The time sensitivity of aspirational interventions: Evidence from a role-modeling RCT

Prateek Chandra Bhan, Max Schroeder, Damiano Turchet, Jinglin Wen

published 15 Jun 2026

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Motherhood choice in multiple sclerosis (MoMS) – Pilot trial of web-based decision support

Lara S. Stahl, Julia Hickstein, Sascha Köpke, Kerstin Hellwig, Christoph Heesen, Anne C. Rahn

published 12 Jun 2026

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