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Randomized controlled trials

A new experimental method for evaluating the effectiveness of auditory signals under realistic background noise conditions: A randomized controlled pilot study

Mako Katagiri, Isuzu Nakamoto, Sayaka Uiji, Tomoko Wakamura

published 08 Apr 2026

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Effects of virtual reality training on racket sports performance: A systematic review and meta-analysis of controlled trials

Rui Liu, Hazwani Ahmad Yusof Hanafi, ZiMei Zhong, Rohayu Hami

published 06 Apr 2026

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Five-year real-world outcomes of short-course leukocyte-poor PRP versus standard conservative therapy in early-stage knee osteoarthritis

Qiuping Yu, Chenghong Wen, Junli Liu

published 02 Apr 2026

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Safety and efficacy of Vectored thermal pulsation, Intense pulsed light, and Eyelid Warm compress therapies (VIEW) for meibomian gland dysfunction: Study design and baseline characteristics of a randomized controlled trial

Zhichao Hu, Hanson Yiu Man Wong, Emily Hoi Ying Chan, Eric Ka Ho Choy, Andy Chak Fung Ng, Xulin Liao, Fatema Mohamed Ali Abdulla Aljufairi, Jake Uy Sebastian, Kenneth Ka Hei Lai, Charlotte Yi Sum Poon, Wanxue Chen, Vanissa Wing See Chow, Clement Chee Yung Tham, Chi Pui Pang, Kelvin Kam Lung Chong

published 02 Apr 2026

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The STRENGTH Study: A cluster randomised controlled trial of the effect of a behaviour change intervention added to cardiac rehabilitation on physical activity adherence

Clare T. M. Doherty, Mark A. Tully, Jason J. Wilson, Leonie Heron, Helen McAneney, Victoria Irving, Lisa Spratt, Rachel O’Reilly, Kim Kensitt, Nicole E. Blackburn

published 24 Mar 2026

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Comparative efficacy and safety of Chinese botanical drug injection in patients with sepsis: A systematic review and Bayesian network meta-analysis of randomized clinical trials

Yue Yuan, Jiajia Wang, Siyuan Lei, Jiansheng Li

published 24 Mar 2026

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Coenrollment of critically ill patients in PROSPECT: A protocol and statistical analysis plan

Alex Thabane, Diane Heels-Ansdell, Nicole Zytaruk, Deborah Cook, for the PROSPECT Investigators and the Canadian Critical Care Trials Group

published 23 Mar 2026

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A randomised controlled feasibility study of the Carers-ID intervention to support the mental health of family carers of people with intellectual disabilities

Rachel A. Leonard, Maria Truesdale, Michael Brown, Lynne Marsh, Stuart Todd, Nathan Hughes, Trisha Forbes, Ashleen Crowe, Mark A. Linden

published 20 Mar 2026

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IMPlementing IMProved Asthma self-management as RouTine (IMP²ART) in UK primary care: An internal pilot for a cluster randomised controlled trial

Kirstie McClatchey, Daisy Bertram, Atena Barat, Brigitte Delaney, Vicky Hammersley, Barbara Korell, Viv Marsh, Megan Preston, Jessica Sheringham, Liz Steed, Steven Julious, David Price, Stephanie J. C. Taylor, Hilary Pinnock

published 20 Mar 2026

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Combined repetitive transcranial magnetic stimulation and functional electrical stimulation cycling to improve lower extremity function following incomplete spinal cord injury: Protocol for a pilot randomized controlled trial

Fereshteh Ghahremani, Siobhan Schabrun, Sue Peters, Laura Brunton, Janelle Unger

published 19 Mar 2026

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Effect of accentuated eccentric loading countermovement jumps and drop jump training with ladder training versus ladder training alone on sprint performance and change of direction ability in futsal players: A randomized controlled trial protocol

Darpan Chaudhari, Swapnil U. Ramteke

published 19 Mar 2026

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Helping primary care providers recognize and respond to medication non-adherence and drug-drug interactions: A randomized-controlled clinical utility trial in a value-based care setting

Trever Burgon, David Paculdo, Joshua Schrecker, Kelsy Gibson Ferrara, Randy E. David, Steven Johnson, Czarlota Valdenor, John W. Peabody

published 16 Mar 2026

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A pilot randomized controlled trial to explore the feasibility of a peer-delivered single-session brief intervention for youth with moderate risk substance use

Florence Jaguga, Matthew Turissini, Edith Kamaru Kwobah, Edith Apondi, Leslie A. Enane, Julius Barasa, Gilliane Kosgei, Yvonne Olando, Mary A. Ott, Allan Kimaina, Matthew C. Aalsma

published 16 Mar 2026

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