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Randomized controlled trials

Methodological insights from the EPISTOP trial to designing clinical trials in rare diseases—A secondary analysis of a randomized clinical trial

Stephanie Wied, Ralf-Dieter Hilgers, [ ... ], Rima Nabbout

Effect of perioperative lidocaine infusion on the subjective quality of recovery after surgery: Protocol for an updated systematic review and meta-analysis

Qianli Huang, Changhui Shao, Wei Wei, Shan Ou

A qualitative exploration into the experience of mindfulness in moderate-severe persistent depression

Timothy Sweeney, Elena Nixon, Richard Morriss, Patrick Callaghan

Comparative effectiveness and safety of insulin reference biologics versus biosimilars for types 1 and 2 diabetes mellitus: Protocol for a systematic review of real-world studies

Martin K. H. Ho, Araniy Santhireswaran, [ ... ], Mina Tadrous

Randomization in clinical trials with small sample sizes using group sequential designs

Daniel Bodden, Ralf-Dieter Hilgers, Franz König

Effectiveness of care provided by an itinerant community caregiver in reducing the burden and violence of family caregivers of impaired elderly in Rio de Janeiro, Brazil: A randomized clinical trial

Valéria Teresa Saraiva Lino, Nadia Cristina Pinheiro Rodrigues, [ ... ], Germana Perisse

Long-term Double-J stenting is superior to short-term Single-J stenting in kidney transplantation

Christiaan A. J. Oudmaijer, Kelly Muller, [ ... ], Turkan Terkivatan

Exploratory outcomes of the DHA WIN randomized controlled trial: Supplementing women with docosahexaenoic acid did not reduce the impact of neoadjuvant breast cancer chemotherapy on quality of life or exercise behaviour

Claire M. Douglas, Marnie Newell, [ ... ], Catherine J. Field

Did a digital quality of life (QOL) assessment and practice support system in home health care improve the QOL of older adults living with life-limiting conditions and of their family caregivers? A mixed-methods pragmatic randomized controlled trial

Richard Sawatzky, Kara Schick-Makaroff, [ ... ], S. Robin Cohen

A systems analysis and improvement approach to optimizing syringe services programs’ delivery of HIV testing and referrals: Study protocol for a parallel-group randomized controlled trial (SAIA-SSP-HIV)

Angela R. Bazzi, Alexis M. Roth, [ ... ], Barrot H. Lambdin

Efficacy and safety profile of combining antiangiogenic agents with chemotherapy in patients with advanced malignant pleural mesothelioma: A systematic review and meta-analysis of randomized controlled trials

Wei Tian, Qian Guo, [ ... ], Rui Wang

The relationship between study findings and publication outcome in anesthesia research following implementation of mandatory trial registration: A systematic review of publication bias

Simon W. Chong, Georgina Imberger, [ ... ], Philip J. Peyton

Effect of intraoperative intravenous remimazolam on the postoperative quality of recovery after noncardiac surgery: A meta-analysis of randomized controlled trials

Huan Liu, Mingxia Zhou, [ ... ], Zhilin Wu

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