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Randomized controlled trials

The effectiveness of smart healthcare for patients with rheumatoid arthritis: A systematic review and meta-analysis

Yin Yu, Meijiao Wang, Hejing Pan, Lin Huang, Haichang Li, Xuanlin Li

published 08 Jan 2026

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The role of online peer support in pregnancy: A scoping review

Honor Morris, Maria Duaso, Marilyn Ijeomah-Orji, Lisa Akester, Jenny Roddy, Jayne Samples, Kate Heighway, Nigel Simpson, Tomasina Stacey

published 02 Jan 2026

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STOPS approach to individualised physiotherapy versus usual physiotherapy care for chronic low back pain in India: A randomised controlled trial protocol

Andrew J. Hahne, Mohini Shah, Muhammed Rashid, Kavitha Raja, Musa Sani Danazumi, Jon Ford

published 30 Dec 2025

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A systematic review of the effectiveness of self-symptoms monitoring with Patient Reported Outcome Measures in rheumatic disease patients

Yu Heng Kwan, Livia Oh, Pui Kim Ang, Zhonghui Xiong, Pei Xin Chong, Sungwon Yoon, Pei Shi Ong, Charmaine T. M. Wang, Silvana X. Choo, Ying Ying Leung, Julian Thumboo, Warren Fong

published 30 Dec 2025

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A scoping review of interventions to prevent and treat adverse events during treatment of rifampin-susceptible tuberculosis

William J. Burman, M. Florencia Martins, David Flynn, James Johnston, Pranay Sinha, C. Robert Horsburgh

published 26 Dec 2025

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Adaptation and evaluation of a digital dialectical behaviour therapy for youth at clinical high risk for psychosis: A protocol for a feasibility randomized controlled trial

Thea Lynne Hedemann, Yun Lu, Sofia Campitelli, Lisa D. Hawke, Nelson Shen, Sarah Saperia, Brett D. M. Jones, Gillian Strudwick, Chelsey R. Wilks, Wei Wang, Marco Solmi, Michael Grossman, Muhammad Ishrat Husain, Nicole Kozloff, George Foussias, Muhammad Omair Husain

published 23 Dec 2025

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Effects of aquatic exercise on arterial stiffness and endothelial function in adults: A systematic review and meta-analyses

Emily Dunlap, Yanbing Zhou, Manny M.Y. Kwok, Billy C.L. So, Hirofumi Tanaka

published 12 Dec 2025

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Safety outcomes of statin vs non-statin lipid-lowering interventions in patients with prior statin-associated muscle symptoms: A systematic review and meta-analysis

Philipp Stefan Aebi, Fanny Villoz, Jonas Bührer, Christina Lyko, Nazanin Abolhassani, Cinzia Del Giovane, Baris Gencer, Nicolas Rodondi, Manuel R. Blum

published 11 Dec 2025

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The effects of high-frequency repetitive transcranial magnetic stimulation on negative symptoms in schizophrenia patients: A systemic review and meta-analysis

Boxing Wang, Xinyue Zhu, Ling Chen, Shuyun Liu, Chengshi Wang

published 11 Dec 2025

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Who gets included? A scoping review protocol of digital health interventions for older adults with heart failure through an equity lens

Kristina M. Kokorelias, Peter Hoang, Maurita T. Harris

published 04 Dec 2025

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Pharmacologic neuroprotective agents for the treatment of perinatal asphyxia in low-income and lower-middle-income countries: A systematic review and meta-analysis of randomised controlled trials

Victor Ayodeji Ayeni, Aisha Adam Abdullahi, Abdulmuminu Isah, Love Bukola Ayamolowo, Timothy Adeyemi, Motunrayo Adebukunola Oladimeji, Ufuoma Shalom Ahwinahwi, Vitalis Ikenna Chukwuike, Oluchukwu Perpetual Okeke, Olunike Rebecca Abodunrin, Folahanmi Tomiwa Akinsolu, Olajide Odunayo Sobande

published 04 Dec 2025

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Evaluation of umbilical cord blood serum eye drops for severe dry eye in two distinct populations—Sjögren’s syndrome and mustard gas–induced ocular injury: Protocol for a pilot randomized clinical trial

Seyed Hashem Daryabari, Hossein Aghamollaei, Seyyed Morteza Hosseini Imeni, Masoud Rostami

published 04 Dec 2025

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Comparison of Atezolizumab plus Aevacizumab and Atezolizumab plus Aabozantinib for advanced hepatocellular carcinoma: A cost-effectiveness analysis

Heng Xiang, Zhihua She, Liting Wang, Ye Peng, Lei Zhang, Chongqing Tan

published 03 Dec 2025

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