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Randomized controlled trials

Process evaluation of a pragmatic, multicentre pilot Randomised Controlled Trial (RCT) in primary care: Tailored intervention for COPD and Co-morbidities by Pharmacists and Consultant Physicians (TICC PCP)

Karen Wood, Richard Lowrie, Georgia Smith, David Anderson, Jane Moir, Lynda Attwood, Andrew McPherson, Aziz Sheikh, Elaine Rankine, Frances S. Mair

published 30 Jun 2025

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Randomised controlled trials for improving health outcomes for people living with multiple long-term conditions: Protocol for a systematic review of methodological approaches, risk of bias and reporting quality

Lisong Zhang, Elizabeth Fisher, Naomi Bradbury, Natalie Darko, Kamlesh Khunti, Selina Lock, Sally J. Singh, Sharon A. Simpson, Ellesha Smith, Susan M. Smith, Rod S. Taylor, Miles Witham, Hannah Young, Laura J. Gray

published 30 Jun 2025

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Effectiveness of interactive dashboards as audit and feedback tools in primary care: A systematic review

Florence L. Meier, Levy Jäger, Oliver Senn, Stefan Markun, Jakob M. Burgstaller

published 27 Jun 2025

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Optimising access to vocational rehabilitation through multiple sclerosis charities: Protocol for a feasibility randomised controlled trial

Blanca De Dios Pérez, Denise Kendrick, Roshan das Nair, Nikos Evangelou, Ian Newsome, Kate Radford

published 27 Jun 2025

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Major adverse cardiac events with haloperidol: A meta-analysis

Michael Cristian Garcia, Mason Anderson, Michelle Li, Mick Zewdu, Tyler Schneider, Jessyca Matos-Silva, Genevieve Ramnarine, Kassie Rong, Lawrence Mbuagbaw, Anne Holbrook

published 25 Jun 2025

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Probiotic bacteria vs. yeast for gastrointestinal diseases treatment: Protocol for a systematic review and meta-analysis

Wardah Alsalemi, Zamri Chik, Mohammed Abdullah Alshawsh

published 24 Jun 2025

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Assessing the latest advances in bone marrow stem cell therapy for Avascular Necrosis hip: A comprehensive systematic review, meta-analysis, and meta-regression of randomized controlled trial studies

Robin Novriansyah, Tanti Ajoe Kesoema, Kevin Christian Tjandra, I. Nyoman Sebastian Sudiasa, Shakira Amirah, Imke Maria Del Rosario Puling, Prudence Lucianus, Revina Maharani, Danendra Rakha Putra Respati, Laksmana Adi Krista Nugraha, Ismail Hadisoebroto Dilogo

published 24 Jun 2025

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The effect of adding neuromuscular electrical stimulation to exercise therapy on patellofemoral pain: A systematic review and meta-analysis

Jiawei Zheng, Zixuan Wei, Huiwu Zuo, Kunpeng Wang, Xikai Lin, Jian Chen

published 23 Jun 2025

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Clinical efficacy and Safety of Baloxavir Marboxil compared with Oseltamivir against influenza virus in children: A systematic review and meta-analysis

Ling Zhu, Li Zhong, Guidong Huang

published 23 Jun 2025

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Emulating the EPIC trial using VetCompass primary-care data: causal effects of pimobendan in UK dogs with grade IV/VI heart murmurs

Camilla Pegram, Karla Diaz-Ordaz, Dave C. Brodbelt, Yu-Mei Chang, Adrian Boswood, Jenny Wilshaw, Carmen A. T. Reep, Sarah Balling, Jaya Sahota, David B. Church, Dan G. O’Neill

published 18 Jun 2025

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Clinical efficacy of different therapeutic options for knee osteoarthritis: A network meta-analysis based on randomized clinical trials

Xiao Chen, Yuanhe Fan, Hongliang Tu, Yuan Luo

published 18 Jun 2025

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Preventing respiratory illness in cerebral palsy: Results of a pilot randomized controlled trial

Ryan J. Coller, Kristina Singh-Verdeflor, Jens Eickhoff, Paul J. Chung, Heidi M. Kloster, Christopher C. Cushing, Danielle M. Gerber, Barbara J. Katz, Siem Ia, Teresa Wagner, Roxana Delgado-Martinez, Gemma Warner, Lorena Porras-Javier, Thomas S. Klitzner, Carlos F. Lerner

published 16 Jun 2025

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On the effect of flexible adjustment of the p value significance threshold on the reproducibility of randomized clinical trials

Farrokh Habibzadeh

published 13 Jun 2025

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