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Purkinje cells

Identification and characterization of two novel KCNH2 mutations contributing to long QT syndrome

Anthony Owusu-Mensah, Jacqueline Treat, Joyce Bernardi, Ryan Pfeiffer, Robert Goodrow, Bright Tsevi, Victoria Lam, Michel Audette, Jonathan M. Cordeiro, Makarand Deo

published 05 Jan 2024

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GAD65 deficient mice are susceptible to ethanol-induced impairment of motor coordination and facilitation of cerebellar neuronal firing

Wataru Matsunaga, Toru Shinoe, Moritoshi Hirono

published 22 May 2023

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A rad50 germline mutation induces tumorigenesis and ataxia-telangiectasia phenotype in a transparent medaka model

Shinichi Chisada, Kouki Ohtsuka, Masachika Fujiwara, Masao Yoshida, Satsuki Matsushima, Takashi Watanabe, Kanae Karita, Hiroaki Ohnishi

published 25 Apr 2023

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Accumulation of senescence observed in spinocerebellar ataxia type 7 mouse model

William Miller, Charles Lewis Humphrey Pruett, William Stone, Cindy Eide, Megan Riddle, Courtney Popp, Matthew Yousefzadeh, Christopher Lees, Davis Seelig, Elizabeth Thompson, Harry Orr, Laura Niedernhofer, Jakub Tolar

published 17 Oct 2022

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A 1 bp deletion in HACE1 causes ataxia in Norwegian elkhound, black

Kim K. L. Bellamy, Fredrik S. Skedsmo, Josefin Hultman, Ellen F. Arnet, Ole Albert Guttersrud, Hege Kippenes Skogmo, Stein Istre Thoresen, Arild Espenes, Karin Hultin Jäderlund, Frode Lingaas

published 21 Jan 2022

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A biochemical mechanism for time-encoding memory formation within individual synapses of Purkinje cells

Ayush Mandwal, Javier G. Orlandi, Christoph Simon, Jörn Davidsen

published 07 May 2021

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Kola nut from Cola nitida vent. Schott administered to pregnant rats induces histological alterations in pups’ cerebellum

Foluso A. Atiba, Amos A. Fatokun, Innocent O. Imosemi, Adefolarin O. Malomo

published 08 Mar 2021

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Anoctamin 2-chloride channels reduce simple spike activity and mediate inhibition at elevated calcium concentration in cerebellar Purkinje cells

Friederike Auer, Eliana Franco Taveras, Uli Klein, Céline Kesenheimer, Dana Fleischhauer, Frank Möhrlen, Stephan Frings

published 02 Mar 2021

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Non-motor symptoms in essential tremor, akinetic rigid and tremor-dominant subtypes of Parkinson’s disease

Ali S. Shalash, Eman Hamid, Hanan Elrassas, Eshak I. Bahbah, Alia H. Mansour, Hadeer Mohamed, Mahmoud Elbalkimy

published 27 Jan 2021

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Cannabinoid type 2 receptors inhibit GABA_A receptor-mediated currents in cerebellar Purkinje cells of juvenile mice

Sriity Melley Sadanandan, Tabita Kreko-Pierce, Shailesh N. Khatri, Jason R. Pugh

published 21 May 2020

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A neonatal nonhuman primate model of gestational Zika virus infection with evidence of microencephaly, seizures and cardiomyopathy

Rosemary J. Steinbach, Nicole N. Haese, Jessica L. Smith, Lois M. A. Colgin, Rhonda P. MacAllister, Justin M. Greene, Christopher J. Parkins, J. Beth Kempton, Edward Porsov, Xiaojie Wang, Lauren M. Renner, Trevor J. McGill, Brandy L. Dozier, Craig N. Kreklywich, Takeshi F. Andoh, Marjorie R. Grafe, Heidi L. Pecoraro, Travis Hodge, Robert M. Friedman, Lisa A. Houser, Terry K. Morgan, Peter Stenzel, Jonathan R. Lindner, Robert L. Schelonka, Jonah B. Sacha, Victoria H. J. Roberts, Martha Neuringer, John V. Brigande, Christopher D. Kroenke, Antonio E. Frias, Anne D. Lewis, Meredith A. Kelleher, Alec J. Hirsch, Daniel Neal Streblow

published 14 Jan 2020

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Loss of prostatic acid phosphatase and α-synuclein cause motor circuit degeneration without altering cerebellar patterning

Maryam Rahimi-Balaei, Matthew Buchok, Pirkko Vihko, Fiona E. Parkinson, Hassan Marzban

published 11 Sep 2019

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Mice lacking EFA6C/Psd2, a guanine nucleotide exchange factor for Arf6, exhibit lower Purkinje cell synaptic density but normal cerebellar motor functions

Shintaro Saegusa, Masahiro Fukaya, Wataru Kakegawa, Manabu Tanaka, Osamu Katsumata, Takeyuki Sugawara, Yoshinobu Hara, Makoto Itakura, Tadashi Okubo, Toshiya Sato, Michisuke Yuzaki, Hiroyuki Sakagami

published 16 May 2019

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