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Proteomics

Comprehensive in silico analysis of genetic landscape and pathways involved in Stickler syndrome

Ravinder Sharma, Kiran Yadav, Vikas Gupta, Anchal Arora, Vikas Yadav

published 20 Feb 2026

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System biology and network-based approach to identify the therapeutic signatures and potential inhibitors against polycystic lipomembranous osteodysplasia with Sclerosing Leukoencephalopathy

Bayan T. Bokhari, Alaa M. Saleh, Hashim M. Aljohani, Wejdan Hussain Owaydhah, Mohammad Ahmad Alobaidy, Naief Dahran, Hind M. Naffadi, Alaa Abdulaziz Eisa

published 20 Feb 2026

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Identification of two terpenoids from Withania coagulans with predicted multitarget binding affinity: An in vitro and in silico study

Hansa Gul, Nasir Assad, Zahida Nasreen, Nouman Ahmad, Yasir Assad, Muhammad Nauman Khan, Ahmed Vandy, Michael Lahai, Muhammad Naeem-ul-Hassan, Sezai Ercişli

published 20 Feb 2026

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Multi-omics analysis identifies PPARα as a key inhibitor of hepatocyte ferroptosis in sepsis-associated liver injury

Shi-Ling He, Jian-Chuan Lin, Gao-Fang Wu, He-fan He

published 19 Feb 2026

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Elucidating key targets and mechanisms of diethyl phthalate-induced colorectal cancer through network toxicology and molecular docking

Zijing Wang, Liyuan Ma, Zhanyuan Sun, Hengyi Lv, Ruxue Ma, Mengqi Ding, Hai Li, Tao Jiang

published 17 Feb 2026

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Development of serologic diagnostic test based on in silico predicted synthetic peptides for Brucella canis in dogs

Monique Ferreira Silva Souza, Lucas dos Reis de Souza, Pamela Aparecida Lima, Tatyane Martins Cirilo, Samuel Alexandre Pimenta Carvalho, Lilian Lacerda Bueno, João Luís Reis Cunha, Tatiane Alves da Paixão, Ricardo Toshio Fujiwara, Renato Lima Santos

published 17 Feb 2026

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Differential protein expression profiles in human sperm from teratozoospermic and normozoospermic men identify LTBP1 and TGF-βR1 as potential biomarkers within the TGF-β signalling pathway

Paweena Kaewman, Sutisa Nudmamud-Thanoi, Patcharada Amatyakul, Chuchard Punsawad, Sittiruk Roytrakul, Samur Thanoi

published 13 Feb 2026

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Precision screening identifies mitoxantrone as a multitarget inhibitor in ageing-associated cancers with extensive computational validation and doxorubicin comparison

Mohammed H. Al-Qahtani, Mourad Assidi, Abdelbaset Buhmeida, Asma Almuhammadi, Peter Natesan Pushparaj, Nofe Ateq Alganmi

published 13 Feb 2026

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In-silico target prediction and pathway analysis of propranolol as a potential therapeutic agent for hepatocellular carcinoma

Ishaq Ahmad, Shakeel Ahmad Khan, Muhammad Abu Bakar, Adnan Shakoor, Abdul Wasy Zia

published 13 Feb 2026

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MAGIN-GO: Protein function prediction based on dual graph neural networks and gene ontology structure

Runxin Li, Wentao Xie, Zhenhong Shang, Xiaowu Li, Guofeng Shu, Lianyin Jia, Wei Peng

published 09 Feb 2026

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Evaluating global measures of network centralization: Axiomatic and numerical assessments

Majid Saberi, Samin Aref

published 05 Feb 2026

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Effects of silybin on triptorelin-induced bone metabolic abnormalities in prostate cancer revealed based on TMT-based proteomics

Jianhui Li, Xuejiao Lv, Ying Jiang

published 29 Jan 2026

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Identifying biomarkers for diagnosis and disease activity monitoring in PSC-IBD and UC through proteomic profiling: A prospective, biomarker discovery single-center study protocol

Ondrej Fabian, Lukas Bajer, Peter Macinga, Jan Brezina, Mojmir Hlavaty, Pavel Drastich, Pavel Wohl, Karel Harant, Pavel Talacko, Eva Sticova, Andrea Vajsova, Alena Bohdanecka, Filip Tichanek, Monika Cahova

published 27 Jan 2026

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