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Proteomics

Emphasizing the role of oxidative stress and Sirt-1/Nrf2 and TLR-4/NF-κB in Tamarix aphylla mediated neuroprotective potential in rotenone-induced Parkinson’s disease: In silico and in vivo study

Dalia H. Abu-Baih, Abeer H. Elmaidomy, Hesham A. Abou-Zied, Nahla Abdelghany Hussien, Manar I. Rasekh, Entesar A. Saber, Sayed Fouad El-sheikh Ali, Mostafa E. Rateb, Omnia Magdy Hendawy, Faisal H. Altemani, Abdullah H. Altemani, Gerhard Bringmann, Usama Ramadan Abdelmohsen, Omnia Hesham Abdelhafez

published 06 Jan 2026

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Integrative multi-omics and network-based machine learning for early diagnosis of Parkinson’s disease

Wei Liu, Lina Xu, Xuejing Wang, Jiuqi Wang

published 06 Jan 2026

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Layer-specific proteomic analysis of human hearts in patients with sudden cardiac death

Yu Kakimoto, Xueting Guan, Atsushi Ueda, Yayoi Kimura, Tomoko Akiyama, Masayuki Tanaka, Haruka Ikeda, Kazuho Maeda, Shotaro Isozaki

published 30 Dec 2025

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Sucrose but not arsenic induce hepatic steatosis which correlates with calpain-1 inhibition

Myrian Velasco, Rosa Isela Ortiz-Huidobro, Ana María Salazar, Marcia Hiriart, Patricia Ostrosky-Wegman, Pablo Pánico

published 30 Dec 2025

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Isolation and characterization of four novel Vibrio parahaemolyticus bacteriophages from oysters

Joud Aldaroub, Chrissy M. Walsky, Rylee E. Ewell, Frank O. Aylward, Ann M. Stevens, Alison Kernell Burke

published 29 Dec 2025

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Antibacterial efficacy of Solanum muricatum aiton metabolites against methicillin-resistant staphylococcus aureus: Insights into bioactive compounds and molecular mechanisms

Sarah Samir, Fathy A. Behery, Mohamed A. Zarka, Ruqaiah I. Bedaiwi, Hesham A. Abou-Zied, Usama Ramadan Abdelmohsen, Rehab Mahmoud Abd El-Baky, Mohamed A. Mawhoup, Mai Mahrous, Reem E. S. Abdelnaem, Gerhard Bringmann, Abeer H. Elmaidomy

published 26 Dec 2025

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A screening strategy for bioactive components from Amaranth: An integrated approach of network pharmacology, molecular docking and molecular dynamics simulation

Zixuan Zhao, Zhengxin Huang, Kaiming Wang, Hua Zhang, Ying Ren, Jinjin Tong

published 26 Dec 2025

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Analysis of molecular mechanism of Chinese medicine Jinhong decoction (JHD) in synergistically treating sepsis and COVID-19 based on network pharmacology

Jinghan Fan, Yang Yang, Fan Zhang, Xiaowei Wu, Jiajun Li, Li Liang, Qi Tang, Bo Yan, Jiancheng Zhang, Xuming Pan, Guangjun Jin, Changlong Wei, Pingping Han, Yuzhou He

published 18 Dec 2025

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Computation suggests that the cell adhesion sub-proteome is enriched for sites of pH-dependence and charge burial

Shalaw Sallah, Jim Warwicker

published 09 Dec 2025

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RETRACTED: Ph-triazole as a therapeutic agent for pancreatic cancer: Synthesis, in silico, and in vitro evaluation

Ningbo Zhang, Xingxing Li, Fangyuan Li, Jianjiang Jin, Ting Zheng, Li Zhou

published 09 Dec 2025

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A multi-mineral intervention to improve disease-related and mechanistic biomarkers in ulcerative colitis patients: Results from a randomized trial

Muhammad N. Aslam, Danielle Kim Turgeon, Henry D. Appelman, Ryan Stidham, Shannon McClintock, Ron Allen, Gillian Moraga, Isabelle Harber, Kara J. Jencks, Molly M. McNeely, Ananda Sen, Karl J. Jepsen, James Varani

published 08 Dec 2025

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Housing environment bilaterally alters transcriptomic profile in the rat hippocampal CA1 region

Azusa Kubota, Kentaro Kojima, Shinnosuke Koketsu, Takayuki Kannon, Takehiro Sato, Kazuyoshi Hosomichi, Yoshiaki Shinohara, Atsushi Tajima

published 04 Dec 2025

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Assessing the chemical profile and biological potentials of Tamarix smyrnensis flower extracts using different solvents by in vitro, in silico, and network methodologies

Erdi Can Aytar, Emine Incilay Torunoğlu, Abidin Gümrükçüoğlu, Saleh Al-Farraj, Alper Durmaz, Mika Sillanpää

published 01 Dec 2025

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