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Proteomics

KG-MACNF: A nonlinear cross-modal fusion model for predicting drug-target interactions via multi-relational embedding and fine-grained structure

Yihan Feng, Xixin Yang, Yuanlin Guan, Jinyao Zhang, Hang Yang, Zhongyu Wang, Qi Cheng

published 09 Sep 2025

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ProteinWeaver: A webtool to visualize ontology-annotated protein networks

Oliver Anderson, Altaf Barelvi, Aden O’Brien, Ainsley Norman, Iris Jan, Anna Ritz

published 05 Sep 2025

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Leveraging dynamic stability to infer regulation in protein-protein interaction networks: A study of infectious vulnerability in COPD

Joyce Reimer, Jeffrey Page, Pranta Saha, Shichen Shen, Xiaoyu Zhu, Shuo Qian, Manoj Mammen, Jun Qu, Sanjay Sethi, Gordon Broderick

published 05 Sep 2025

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New insights into the molecular biology of Alzheimer’s-like cerebral amyloidosis achieved through multi‐omics approaches

Lorenzo Campanelli, Juan M. Sendoya, Scott Brody, Pablo Galeano, Sonia Do Carmo, A. Claudio Cuello, Eduardo M. Castaño, Andrés Gonzalés-Jimenez, Julia Verheul, Dina Medina-Vera, Fernando Rodríguez de Fonseca, Rasmus Wernersson, Laura Morelli

published 03 Sep 2025

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Identification of immune-related biomarkers associated with allergic rhinitis and development of a sample diagnostic model

MaoMeng Wang, Shuang Wang, XinHua Lin, XiaoJing Lv, XueXia Liu, Hua Zhang

published 03 Sep 2025

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Charantin targets HMGCR-PCSK9 axis and activates PPAR-α signaling to ameliorate hyperlipidemia: Mechanistic insights from bioinformatics and in-vivo studies

Ghulam Abbas, Muhammad Nasir Hayat Malik, Haya Yasin, Saud O. Alshammari, Ghulam Murtaza, Waseem Hassan, Muhammad Atif, Ramla Shabbir

published 02 Sep 2025

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Unearthing prehistoric diets: First evidence of horse meat consumption in Early Bronze Age Sicily

Davide Tanasi, Roberto Micciché, Robert H. Tykot, Luis Busetti, Pierluigi Barbieri, Gianpiero Di Maida, Viviana Ardesia, Alessandro Miani, Elia Marin, Enrico Greco

published 29 Aug 2025

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Critical node detection in temporal social networks, based on global and semi-local centrality measures

Zahra Farahi, Rooholah Abedian, Luis E. C. Rocha, Ali Kamandi

published 26 Aug 2025

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Integrative molecular network analysis of genetic risk factors to infer biomarkers and therapeutic targets for rheumatoid arthritis

Sakhaa Alsaedi, Katsuhiko Mineta, Naoto Tamura, Xin Gao, Takashi Gojobori, Michihiro Ogasawara

published 21 Aug 2025

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Integrated gene network analysis and experimental validation identify key hub genes in potato response to Potato Virus Y infection

Roya Karimipour, Davoud Koolivand, Abozar Ghorbani, Masoud Naderpour, Mahsa Rostami

published 14 Aug 2025

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Comparative proteomics of HepG2 cells reveals NGLY1 as an important regulator of ferroptosis resistance and iron uptake

Stuart Emmerson, Haruhiko Fujihira, Takehiro Suzuki, Naoshi Dohmae, Peter Greimel, Yoshio Hirabayashi, Tadashi Suzuki

published 14 Aug 2025

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Influential node identification method based on multi-order neighbors and exclusive neighborhood

Feifei Wang, Zejun Sun, Guan Wang, Bohan Sun

published 13 Aug 2025

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Multi-Omics insights into the molecular mechanisms of trochlear dysplasia: A proteomic and metabolomic study in rats

Zhenhui Huo, Huijun Kang, Peishuo Liu, Yanshuo Li, Yingzhen Niu, Kuo Hao, Chongyi Fan, Fei Wang, Wei Lin

published 11 Aug 2025

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