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Protein-protein interactions

Bacteriophage T4 gene 32 protein: Insights into its interaction with ssDNA, binding cooperativity, and conformational change

Jules Guei, Michael P. Chapman, Paul N. Brothers, Shital Desai, Richard L. Karpel

published 11 Feb 2026

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Integrative multi-omics analyses identify key genes and elucidate bidirectional regulatory mechanisms in thyroid dysfunction

Yilang Hu, Hong Hu, Lijun Xu, Xuzheng Tang, Chongyu Wang, Zhengyi Lian, Chenyu Xie, Zhiwan Xie, Qingqing Wang

published 22 Jan 2026

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Leveraging dynamic stability to infer regulation in protein-protein interaction networks: A study of infectious vulnerability in COPD

Joyce Reimer, Jeffrey Page, Pranta Saha, Shichen Shen, Xiaoyu Zhu, Shuo Qian, Manoj Mammen, Jun Qu, Sanjay Sethi, Gordon Broderick

published 05 Sep 2025

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Protein-protein interaction prediction using bidirectional GRUs with explicit ensemble

Qiuhong Lan, Zhongtuan Zheng, Zhen Tang, Xuehua Qiu, Zhixiang Yin

published 02 Jul 2025

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Transcriptomic profiling of pancreatic neuroendocrine tumors: dysregulation of WNT, MAPK, PI3K, neddylation pathways and potential non-invasive biomarkers

Helvijs Niedra, Olesja Rogoza, Rihards Saksis, Raitis Peculis, Anzela Halilova, Aija Gerina, Sofija Vilisova, Natalja Senterjakova, Aldis Pukitis, Ignacio Ruz-Caracuel, Julie Earl, Georgina Kolnikova, Peter Dubovan, Miroslav Tomas, Peter Makovicky, Maria Urbanova, Bozena Smolkova, Eythimios Koniaris, Ioanna Aggelioudaki, Agapi Kataki, Vita Rovite

published 16 Jun 2025

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Polypyrimidine tract binding proteins PTBP1 and PTBP2 associate with distinct proteins and have distinct post-translational modifications in neuronal nuclear extract

Michael E. Sullivan, Jacob A. Edberg, Christopher I. Nunez, Herbert L. Axelrod, Niroshika M. Keppetipola

published 04 Jun 2025

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Genetic variations and recurrence in stage III Korean colorectal cancer: Insights from tumor-only mutation analysis

Hajin Jeon, Jong Lyul Lee, Hyeran Shim, Soobok Joe, Iksu Byeon, Chan Wook Kim, Seok-Byung Lim, In Ja Park, Yong Sik Yoon, Hoang Bao Khanh Chu, Young-Joon Kim, Chang Sik Yu, Jin Ok Yang

published 23 May 2025

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In silico studies provide new structural insights into trans-dimerization of β₁ and β₂ subunits of the Na⁺, K⁺-ATPase

Gema Ramírez-Salinas, Liora Shoshani, Jorge L. Rosas-Trigueros, Christian Sosa Huerta, Marlet Martínez-Archundia

published 29 Apr 2025

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Methylome and transcriptome analyses reveal HLA-DMB’s contribution to periodontitis development

Bo Zhao, Ronghua Li

published 23 Apr 2025

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Analysis of cellular senescence-related genes in calcified aortic valve disease and the potential therapeutic role of β-Carotene

Yijing Tao, Chengjie Gao, Juan Wang, Qiyin Zhang, Zhisong Wang, Leng Han, Donglai Cao, Qianwen Yao

published 10 Mar 2025

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Modelling protein-protein interactions for the design of vaccine chimeric antigens with protective epitopes

Marinela Contreras, Marta Rafael, Isidro Sobrino, Consuelo Almazán, Juan J. Pastor Comín, James J. Valdés, Carlos Roberto Prudencio, Daniel Ferreira de Lima Neto, Veniamin A. Borin, Pratul K. Agarwal, Paul D. Kasaija, Rubén Fernández-Melgar, Justus Rutaisire, José de la Fuente

published 10 Feb 2025

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Site-selective photo-crosslinking for the characterisation of transient ubiquitin-like protein-protein interactions

Zac Sandy, Zijuan Wang, Deepak Behera, Benjamin M. Foster, Finlay A. Martin, Kira Brüninghoff, Kathleen M. Cain, Wolfgang Dörner, Maria Jose Cabello-Lobato, Josep V. Forment, Matthew J. Cliff, Igor Larrosa, Perdita Barran, Duncan L. Smith, Henning D. Mootz, Christine K. Schmidt

published 27 Jan 2025

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Integration of biological data via NMF for identification of human disease-associated gene modules through multi-label classification

Syed Alberuni, Sumanta Ray

published 12 Dec 2024

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