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Proteasomes

The Type II Hsp40 Sis1 Cooperates with Hsp70 and the E3 Ligase Ubr1 to Promote Degradation of Terminally Misfolded Cytosolic Protein

Daniel W. Summers, Katie J. Wolfe, Hong Yu Ren, Douglas M. Cyr

published 16 Jan 2013

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Alterations of the Intracellular Peptidome in Response to the Proteasome Inhibitor Bortezomib

Julia S. Gelman, Juan Sironi, Iryna Berezniuk, Sayani Dasgupta, Leandro M. Castro, Fabio C. Gozzo, Emer S. Ferro, Lloyd D. Fricker

published 07 Jan 2013

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Exercise Training Prevents TNF-α Induced Loss of Force in the Diaphragm of Mice

Norman Mangner, Axel Linke, Andreas Oberbach, Yvonne Kullnick, Stephan Gielen, Marcus Sandri, Robert Hoellriegel, Yasuharu Matsumoto, Gerhard Schuler, Volker Adams

published 02 Jan 2013

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Exercise Training Restores Cardiac Protein Quality Control in Heart Failure

Juliane C. Campos, Bruno B. Queliconi, Paulo M. M. Dourado, Telma F. Cunha, Vanessa O. Zambelli, Luiz R. G. Bechara, Alicia J. Kowaltowski, Patricia C. Brum, Daria Mochly-Rosen, Julio C. B. Ferreira

published 27 Dec 2012

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Inhibition of the Host Proteasome Facilitates Papaya Ringspot Virus Accumulation and Proteosomal Catalytic Activity Is Modulated by Viral Factor HcPro

Nandita Sahana, Harpreet Kaur, Basavaraj, Fatima Tena, Rakesh Kumar Jain, Peter Palukaitis, Tomas Canto, Shelly Praveen

published 27 Dec 2012

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HDAC Inhibitor L-Carnitine and Proteasome Inhibitor Bortezomib Synergistically Exert Anti-Tumor Activity In Vitro and In Vivo

Hongbiao Huang, Ningning Liu, Changshan Yang, Siyan Liao, Haiping Guo, Kai Zhao, Xiaofen Li, Shouting Liu, Lixia Guan, Chunjiao Liu, Li Xu, Change Zhang, Wenbin Song, Bing Li, Ping Tang, Q. Ping Dou, Jinbao Liu

published 20 Dec 2012

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Heterologous SUMO-2/3-Ubiquitin Chains Optimize IκBα Degradation and NF-κB Activity

Fabienne Aillet, Fernando Lopitz-Otsoa, Isabel Egaña, Roland Hjerpe, Paul Fraser, Ron T. Hay, Manuel S. Rodriguez, Valérie Lang

published 20 Dec 2012

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Structural and Functional Analysis of Multi-Interface Domains

Liang Zhao, Steven C. H. Hoi, Limsoon Wong, Tobias Hamp, Jinyan Li

published 14 Dec 2012

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Systemic Perturbation of the ERK Signaling Pathway by the Proteasome Inhibitor, MG132

Murat Cirit, Kyle G. Grant, Jason M. Haugh

published 30 Nov 2012

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Withaferin A Induces Proteasome Inhibition, Endoplasmic Reticulum Stress, the Heat Shock Response and Acquisition of Thermotolerance

Saad Khan, Ashley W. Rammeloo, John J. Heikkila

published 30 Nov 2012

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Bortezomib Is Cytotoxic to the Human Growth Plate and Permanently Impairs Bone Growth in Young Mice

Emma Eriksson, Farasat Zaman, Dionisios Chrysis, Henrik Wehtje, Terhi J. Heino, Lars Sävendahl

published 30 Nov 2012

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Fission Yeast 26S Proteasome Mutants Are Multi-Drug Resistant Due to Stabilization of the Pap1 Transcription Factor

Mary Penney, Itaru Samejima, Caroline R. Wilkinson, Christopher J. McInerny, Søs G. Mathiassen, Mairi Wallace, Takashi Toda, Rasmus Hartmann-Petersen, Colin Gordon

published 27 Nov 2012

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HUWE1 and TRIP12 Collaborate in Degradation of Ubiquitin-Fusion Proteins and Misframed Ubiquitin

Esben G. Poulsen, Cornelia Steinhauer, Michael Lees, Anne-Marie Lauridsen, Lars Ellgaard, Rasmus Hartmann-Petersen

published 27 Nov 2012

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