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Proteases

Structure-based pharmacophore modeling, high-throughput screening, and molecular dynamics identify a novel DrugBank-derived HIV-1 protease inhibitor

Ali Sultan Khazaal Nazal, Amjed Majid Rashid Alrashedi, Lamia Abdultef Risan Al-Iessa, Mustafa Abdulkadhim Hussein Ali Rabeea

published 12 Jun 2026

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The emergence of NDM-1, IMP-7, IMP-26, IMP-62, IMP-76, VIM-4 and VIM-5 producing Pseudomonas aeruginosa strains, identification of a novel sequence type (ST3891) and analysis of virulence genes from a Malaysian tertiary hospital

Kalaivani Kalai Chelvam, Yue Min Lim, Cindy Shuan Ju Teh, Sasheela Ponnampalavanar, Jamuna Vadivelu, Vanitha Mariappan, Kumutha Malar Vellasamy

published 10 Jun 2026

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Integrating preliminary test and Stein-type techniques to improve estimation in the time-dependent Cox model

Rohollah Ramezani, Mohammad Reza Rabiei, Mohammad Arashi

published 08 Jun 2026

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HIV-1 genetic diversity and reverse transcriptase resistance mutations in Benin before dolutegravir era, West Africa

Edmond Tchiakpe, René Kpemahouton Keke, Patricia Recordon-Pinson, Abou Abdallah Malick Diouara, Marie-Line Andreola, Moussa Bachabi, Aldric Afangnihoun, Eric Gbaguidi, Sophia Osawe, Almoustapha Issiaka Maiga, Halimatou Diop-Ndiaye, Coumba Touré-Kane, Akadiri Yessoufou

published 21 May 2026

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In-vitro studies of phytochemical, Antioxidant, Antibacterial and Enzymatic inhibition of Oxalis corniculata whole plant from South Waziristan Tribal District Pakistan

Inayat Ullah, Noor Shad Bibi, Abdul Sadiq, Bakhtyar Niazy, Atiq Mohammad Hesam

published 14 May 2026

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Extracellular activity of a bacterial protease associated with reduced phage infectivity

Ehud Herbst, Gael Rosen Blechman, Taya Fedorenko, Sarah Melamed, Gil Amitai, Rotem Sorek

published 14 May 2026

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A food-grade cell dissociation agent via regulatory pre-check framework

Hiroaki Hatano, Misaki Sawada, Misaki Kitsukawa, Azusa Hayakawa, Hiroaki Kondo, Ikko Kawashima

published 13 Apr 2026

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Inhibition of Chikungunya virus nsP2 protease in vitro by scorpion venom peptide pantinin-1

Mohammadamin Mastalipour, Mônika Aparecida Coronado, Jorge Enrique Hernández González, Dieter Willbold, Raphael Josef Eberle

published 09 Apr 2026

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Identification of BmSP25 gene in Bombyx mori with antiviral function against BmNPV

Yonghong Zhang, Yajin Li, Zhengqin Wang, Jiafu Luo, Lingli Li, Hongrui Zhang

published 27 Mar 2026

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Establishment of an in vitro hairless guinea pig dermal model

Samantha Emma Sarles, Priscilla Lee, Linnzi Wright, Daniel Angelini

published 27 Mar 2026

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Maternal prothrombin time as an independent predictor of neonatal sepsis: A retrospective case–control study

Gökçenur Karakelleoğlu, Elif Ceren Nur Kırımlı Yanık, Şenol Bozdağ

published 20 Mar 2026

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Predatory activity and nematocidal compounds released into liquid culture filtrates as attack strategies of a Mexican strain of Arthrobotrys oligospora against Haemonchus contortus infective larvae

Héctor Alejandro de la Crúz-Crúz, Rosa Isabel Higuera-Piedrahita, Yazmín Alcalá-Canto, Alejandro Zamilpa, Ana Yuridia Ocampo-Gutiérrez, Luis David Arango-de la Pava, Gerardo Ramírez-Rico, Génesis Andrea Bautista-García, Gustavo Pérez-Anzúrez, Agustín Olmedo-Juárez, María Manuela Reyes-Estebanez, Pedro Mendoza de Gives

published 12 Mar 2026

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Functional study of two flexible regions of the hepatitis E virus ORF1 replicase

Léa Mézière, Sonia Fieulaine, Claire Montpellier, Martin Ferrié, Thibault Tubiana, Gabriel Vanegas Arias, Stéphane Bressanelli, Laurence Cocquerel, Cécile-Marie Aliouat-Denis

published 10 Mar 2026

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